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CILNIDIPINE
SynDRA canonical compound SYN0011598 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CACNA1B | CACNA1C |
|---|
| Mechanism of action | calcium channel blocker |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- CACNA1C
- CACNA1B
- CACNA1D
- CACNA1F
- CACNA1S
- CACNA1H
- Cacna1b
Mechanisms of action (all sources)
- CACNA1C BLOCKER
- Voltage-gated L-type calcium channel blocker
- CACNA1S BLOCKER
- CACNA1D BLOCKER
- CACNA1F BLOCKER
- calcium channel blocker
- CACNA1B BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR3C1
- ADORA3
- NR1I2
- PDE4D
- MAOA
- NPY1R
- NFE2L2
- MLNR
- MC3R
- ADORA1
- OPRD1
- HTT
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- KCNH2
- OPRK1
- HRH3
- OPRM1
- PDE3A
- PGR
- PTGS2
- SAMHD1
- SCN5A
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- TDP1
- HTR1A
- HRH2
- ADORA2A
- CBX1
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- IFNB1
- TOR1A
- SMAD3
- SMAD2
- RARA
- PRKN
- PRGR
- PPARG
- NSD2
- NR1H4
- NF2L2
- IFNG
- HLAB
- ANDR
- GEMI
- GCR
- ESRRA
- ESR2
- ESR1
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- TSHR
Drug classes
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Membrane Transport Modulators
ATC classes
- C08C · SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Cross-references
Synonyms
- FRC-8653
- cinaldipine
- cinalong
- Cilnidipino
- Atelec
- Cinalong
- Siscard
- Cinaldipine
- Cilnidipine [INN]
- Atelec (TN)
- Cilnidipine (JAN/INN)
- (+-)-(E)-Cinnamyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (2E)-3-phenyl-2-propenyl ester
- 2-methoxyethyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- FRC 8653
- cilnidipino
- CHEBI:31399
- DTXCID8026309
- cilnidipinum
- RefChem:5688
- C08CA14
- Cilnidipine, (+)-
- Cilnidipine, (-)-
- MFCD00865853
- 4LNU2SU262
- S85436ZG85
- NCGC00162150-01
- (+)-FRC-8653
- (-)-FRC-8653
- CAS-132203-70-4
- SR-05000001454
- UNII-97T5AZ1JIP
- Cilnidipine?
- Cilnidipine (Standard)
- CILNIDIPINE [MI]
- CILNIDIPINE [JAN]
- Cilnidipine (JP18/INN)
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