← SynDRA
TAE-684
SynDRA canonical compound SYN0011451 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ALK |
|---|
| Mechanism of action | ALK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- ALK INHIBITOR
- ALK tyrosine kinase receptor inhibitor
- INSR INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PIK3CG
- PIK3CB
- PIK3CA
- PIK3C2G
- PIK3C2B
- PI4KB
- PHKG2
- PHKG1
- PDPK1
- PDK1
- PDGFRB
- PDGFRA
- PBK
- PAK6
- PAK5
- PAK4
- PAK3
- PAK2
- PAK1
- OXSR1
- NUAK2
- NUAK1
- PIK3CD
- PIM1
- NTRK2
- PIM2
- PRKCH
- PRKCG
- PRKCE
- PRKCD
- PRKCA
- PRKACB
- PRKACA
- PRKAA2
- PRKAA1
- PLK4
- PLK3
- PLK2
- PLK1
Cross-references
Synonyms
- NVP-TAE684
- NVP-TAE 684
- TAE684
- TAE 684
- 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine
- TAE684 (NVP-TAE684)
- UNII-EH1713MN4K
- CHEMBL509032
- EH1713MN4K
- 5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
- C30H40ClN7O3S
- NVT-TAE-684
- RefChem:1072816
- DTXCID90149492
- MFCD11977634
- BDBM50242742
- NVP-TAE684-TAE 684
- GUI
- Kinome_1205
- Nv--tae684
- MLS006010970
- NVP-TAE684?
- SCHEMBL282775
- GTPL5714
- orb1305894
- SCHEMBL29641017
- CHEBI:91338
- EX-A427
- BDBM482158
- GLXC-90064
- HMS3265E03
- HMS3265E04
- HMS3265F03
- HMS3265F04
- US10647694, Example 36
- NSC764041
- s1108
- AKOS005145672
- CCG-270242
Look up TAE-684 in the interactive SynDRA portal →