← SynDRA

ICOSAPENT

SynDRA canonical compound SYN0011254 — structure-anchored drug synonym record

All known targets

• PPARD
• PPARG
• PTGS1
• PTGS2
• ACSL3
• ACSL4
• CYP19A1
• F3
• FADS1
• FFAR1
• OXER1
• PPARA

Mechanisms of action (all sources)

• platelet aggregation inhibitor
• DGAT1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ACHE
• ADORA3
• MAOA
• OPRM1
• PDE3A
• PDE4A
• PGR
• POLK
• POLL
• RGS4
• SLC6A2
• SLC6A3
• SLC6A4
• SREBF2
• TBXA2R
• TDP1
• USP1
• KMT2A
• KDR
• KCNH2
• DRD1
• ADRA1A
• ADRA2A
• ALDH1A1
• AR
• CHRM1
• CHRM2
• DRD3
• HTR2B
• EHMT2
• ESR1
• F2
• GLS
• HRH3
• HTR1A
• VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• GLSK

Drug classes

• Hematologic Agents
• Lipid Regulating Agents
• Platelet Aggregation Inhibitors

Cross-references

• PubChem CID: 446284
• ChEMBL: CHEMBL460026
• DrugBank: DB00159
• ChEBI: CHEBI:36006
• KEGG: D08061
• RxNorm: 90
• PDB: EPA
• Wikipedia: Eicosapentaenoic acid

Synonyms

• eicosapentaenoic acid
• icosapentaenoic acid
• timnodonic acid
• Icosapento
• Eicosapentaenoic acid
• All-cis-fatty acid 20:5 omega-3
• C20:5 (n-3)
• Eicosapentaenoate
• Eicosapentaenoic acid (c20:5 n3)
• Incromega e 7010sr
• Ropufa 70
• Timnodonic acid
• EPA 45G
• EPA
• (all-Z)-5,8,11,14,17-Eicosapentaenoic acid
• all-cis-fatty acid 20:5 omega-3
• EICOSAPENTAENOIC ACID (EPA) (C20:5 N3)
• AAN7QOV9EA
• eicosapentaenoate
• eicosapentaenoic acid (usp-rs)
• (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid
• Icosapentum
• Miraxion
• Eye-Q
• CCRIS 3279
• UNII-AAN7QOV9EA
• EPA [drug]
• (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate
• Icosapentum [INN-Latin]
• Icosapento [INN-Spanish]
• C20:5n-3,6,9,12,15
• CHEBI:28364
• EPA (drug)
• Icosapentum (INN-Latin)
• Icosapento (INN-Spanish)
• RELIVEN
• EPA-FFA
• RefChem:5900

Reported adverse events

• Abdominal discomfort
• Blood triglycerides increased