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BAY-11-7085
SynDRA canonical compound SYN0009274 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | NFKBIA |
|---|
| Mechanism of action | NFkB pathway inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- MAOA
- NPSR1
- NPC1
- MPHOSPH8
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- LMNA
- NPY2R
- LCK
- KCNH2
- KAT2A
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HSPA5
- HRH2
- HRH1
- HPGD
- HMGCR
- NPY1R
- NR3C1
- GMNN
- SIGMAR1
- VDR
- TRPV1
- TDP1
- TBXAS1
- TACR2
- TACR1
- SNCA
- SMN1
Cross-references
Synonyms
- Bay 11-7085
- bay11-7085
- BAY-117085
- 3-((4-(1,1-dimethylethyl)phenyl)sulfonyl)-2-propenenitrile
- CHEBI:176500
- BAY 11-7083
- RefChem:561135
- DTXCID201475587
- (E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile
- (E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile
- (E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile
- MFCD01862602
- (E)-3-(4-t-Butylphenylsulfonyl)-2-propenenitrile
- (2E)-3-(4-tert-butylbenzene-1-sulfonyl)prop-2-enenitrile
- SR-01000075721
- Lopac0_000183
- SCHEMBL157756
- orb1307063
- CHEBI:107653
- GLXC-05947
- HMS3260F07
- HMS3268A22
- HMS3414M13
- HMS3678M13
- EX-A2030
- WHA30976
- Bay 11-7085?
- Tox21_500183
- FD5033
- s7352
- AKOS016014648
- BAY 117083
- CCG-204278
- CS-6316
- DS-6861
- LP00183
- SDCCGSBI-0050171.P002
- NCGC00025271-02
- NCGC00025271-03
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