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BRIVANIB ALANINATE
SynDRA canonical compound SYN0009250 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | FGFR1 | FGFR3 | FLT1 | KDR |
|---|
| Mechanism of action | FGFR inhibitor | VEGFR inhibitor |
|---|
All known targets
- FGFR3
- FGFR1
- FLT1
- KDR
- FGFR2
- FGFR4
- FLT4
- CYP3A4
- KCNH2
Mechanisms of action (all sources)
- FGFR3 INHIBITOR
- Fibroblast growth factor receptor inhibitor
- FGFR1 INHIBITOR
- FGFR4 INHIBITOR
- FGFR2 INHIBITOR
- FLT1 INHIBITOR
- Vascular endothelial growth factor receptor inhibitor
- FLT4 INHIBITOR
- KDR INHIBITOR
- FGFR inhibitor
- VEGFR inhibitor
- KDR MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DDR1
- PDGFRB
- SLK
- STK10
- NUAK2
- RET
- MAP4K4
- PRKAG2
- PRKAG1
- PRKCB
- PRKCA
- OPA1
- PAICS
- PAK2
- PAK4
- PAK6
- PASK
- PCYT1A
- PRKAR2A
- PDXK
- PEBP1
- PFKP
- PHKG2
- PIM1
- PIM2
- NQO2
- PIP4K2A
- PIP4K2C
- PKMYT1
- PKN1
- PKN2
- PKN3
- PLK4
- PRKAA1
- PRKACA
- PRKACB
- PRKACG
- NTRK1
- AAK1
- NLK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Alaninate de brivanib
- Alaninato de brivanib
- Brivanib l-alanine ester
- BMS-582664
- BMS-582664-02
- BMS 582664
- BMS582664
- BMS-582664, Brivanib alaninate
- Brivanib alaninate (INN/USAN)
- L-Alanine, (1R)-2-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yl)oxy)-1-methylethyl ester
- alaninate de brivanib
- alaninato de brivanib
- alaninati brivanibum
- U2Y5OFN795
- CHEBI:167656
- RefChem:917575
- DTXCID20137786
- Brivanib alaninate (BMS-582664)
- UNII-U2Y5OFN795
- Brivanib (alaninate)
- Brivanib alaninateBMS-582664
- brivanib alinate
- Brivanib alaninate [USAN:INN]
- SCHEMBL483382
- GTPL8097
- orb1305304
- BRIVANIB ALANINATE [INN]
- BRIVANIB ALANINATE [JAN]
- SCHEMBL29355920
- BRIVANIB ALANINATE [USAN]
- EX-A012
- Brivanib alaninate,BMS-582664
- GLXC-90234
- BRIVANIB ALANINATE [WHO-DD]
- Brivanib alaninate (JAN/USAN/INN)
- NSC764481
- NSC799369
- s1138
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