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GW632580X
SynDRA canonical compound SYN0009012 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CSF1R |
|---|
| Mechanism of action | cFMS kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- CSF1R INHIBITOR
- NTRK1 INHIBITOR
- NTRK2 INHIBITOR
- NTRK3 INHIBITOR
- cFMS kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SYK
- PDPK1
- PIM1
- PIK3CG
- PIK3CD
- PIK3CB
- PIK3CA
- PIK3C2G
- PIK3C2B
- PI4KB
- PHKG2
- PHKG1
- AAK1
- PIM3
- PDK4
- PDK1
- PDGFRB
- PDGFRA
- PBK
- PASK
- PAK6
- PAK5
- PAK4
- PAK3
- PIM2
- PIP4K2B
- PAK1
- PRKACA
- PRKCZ
- PRKCQ
- PRKCI
- PRKCH
- PRKCG
- PRKCE
- PRKCD
- PRKCB
- PRKCA
- PRKACB
- PRKAA2
- PIP4K2C
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- GW-2580
- GW2580
- cFMS receptor tyrosine kinase inhibitor
- SRV0JCF9LI
- RefChem:144811
- DTXCID10158586
- MFCD12024701
- cFMS Receptor Tyrosine Kinase Inhibitor
- UNII-SRV0JCF9LI
- Kinome_3757
- 4at5
- SC-203877
- GTPL5685
- orb1305208
- SCHEMBL4326587
- SCHEMBL29356034
- SCHEMBL29411766
- BDBM32362
- EX-A579
- cid_11617559
- MYQAUKPBNJWPIE-UHFFFAOYSA-N
- GLXC-05098
- HMS3229E11
- HMS3303G12
- HMS3305H21
- HMS3653B06
- HMS3673K11
- NSC756292
- s8042
- AKOS022179064
- CCG-206754
- CS-3490
- FM31223
- NSC-756292
- SB19390
- SDCCGGSK-0000188.P001
- SDCCGSBI-0086677.P004
- NCGC00242051-01
- NCGC00242051-05
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