← SynDRA

PENCICLOVIR

SynDRA canonical compound SYN0009007 — structure-anchored drug synonym record

All known targets

• HSV UL30
• TK
• TK1
• UL23

Mechanisms of action (all sources)

• DNA directed DNA polymerase inhibitor
• HSV UL30 INHIBITOR
• TK1 INHIBITOR
• DNA polymerase inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ACHE
• OPRK1
• NR3C1
• NPY2R
• NPY1R
• MMP9
• MMP1
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• MAOA
• LCK
• KDR
• KCNH2
• HTR6
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH3
• HRH2
• HRH1
• OPRD1
• OPRM1
• HDAC6
• PDE3A
• TDP1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC6A2
• SLC22A8
• SLC22A7
• SLC22A6

Drug classes

• DNA Polymerase Inhibitors
• Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor
• Anti-Infective Agents
• Antiviral Agents
• Enzyme Inhibitors
• Nucleic Acid Synthesis Inhibitors
• Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor

ATC classes

• J05A · DIRECT ACTING ANTIVIRALS
• D06B · CHEMOTHERAPEUTICS FOR TOPICAL USE
• S01A · ANTIINFECTIVES

Cross-references

• PubChem CID: 135398748
• ChEMBL: CHEMBL1540
• DrugBank: DB00299
• ChEBI: CHEBI:7956
• KEGG: D02124
• RxNorm: 59839
• PDB: PE2
• Wikipedia: Penciclovir
• TTD: D07BYK
• LINCS BRD: BRD-K47780086

Synonyms

• DENAVIR
• Denavir
• denavir
• penciclovir sodium
• BRL-39123
• NSC-759624
• Fenistil
• Vectavir
• Penciclovirum
• Penciclovirum [INN-Latin]
• Pencyclovir
• BRL 39123
• Penciclovir [USAN:INN:BAN]
• Penciceovir
• UNII-359HUE8FJC
• CCRIS 9213
• PE2
• penciclovir (usp impurity)
• NSC 759624
• 9-(4-Hydroxy-3-(hydroxymethyl)butyl)guanine
• 9-(4-HYDROXY-3-(HYDROXYMETHYL)BUT-1-YL)GUANINE
• 9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine
• 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
• CHEBI:7956
• DTXCID7026491
• 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine
• 9-(2-hydroxy-1-(hydroxymethyl)-ethoxymethyl)guanine
• RefChem:55824
• D06BB06
• J05AB13
• MFCD00866931
• NCGC00164630-01
• PCV
• Adenovir
• SMR000466317
• Denavir (TN)
• CAS-39809-25-1

Reported adverse events

• Nausea
• Pruritus
• Thrombocytopenia
• Urticaria
• Vomiting
• Palpitations
• Dizziness
• Fatigue
• Flatulence
• Leukopenia
• Migraine
• Neutropenia