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TENOFOVIR DISOPROXIL
SynDRA canonical compound SYN0009002 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP1A2 | CYP3A4 |
|---|
| Mechanism of action | nucleoside reverse transcriptase inhibitor |
|---|
| Indication | hepatitis B | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP1A2
- CYP3A4
- HIV RT
- gag-pol
- pol
- GAG-POL
- HIV IN
- reverse transcriptas
- HBcAg
Mechanisms of action (all sources)
- nucleoside reverse transcriptase inhibitor
- HIV RT MODULATOR
- pol INHIBITOR
- HIV integrase INHIBITOR
- hiv gag INHIBITOR
- HIV RT INHIBITOR
- HIV IN INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP3A4
- CP3A7
- IFNG
- KSYK
- NF2L2
- SYK
Drug classes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
- Reverse Transcriptase Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- ATRIPLA
- CIMDUO
- COMPLERA
- DELSTRIGO
- EFAVIRENZ, EMTRICITABINE, AND TENOFOVIR DISOPROXIL FUMARATE
- EFAVIRENZ, LAMIVUDINE AND TENOFOVIR DISOPROXIL FUMARATE
- EFAVIRENZ; EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE
- EFAVIRENZ; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE
- EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE
- EMTRICITABINE, RILPIVIRINE AND TENOFOVIR DISOPROXIL FUMARATE
- LAMIVUDINE AND TENOFOVIR DISOPROXIL FUMARATE
- STRIBILD
- viread
- tenofovir disoproxil fumarate
- Tenofovir bis(isopropyloxycarbonyloxymethyl) ester
- (r)-bis(poc)pmpa
- Bis-poc-pmpa
- GS-4331
- Tenofovir disoproxil component of stribild
- Viread
- Bis(POC)PMPA
- bis-POC-PMPA
- tenofovir bis(isopropyloxycarbonyloxymethyl) ester
- F4YU4LON7I
- CHEBI:63717
- STRIBILD COMPONENT TENOFOVIR DISOPROXIL
- RefChem:187852
- DTXCID2031249
- C19H30N5O10P
- MFCD00952920
- UNII-F4YU4LON7I
- Tenofovir disoproxil Impurity 1
- SCHEMBL52793
- MLS006010919
- orb1300062
- SCHEMBL29376425
- BDBM77145
Reported adverse events
- Lactic acidosis
- Lactic acid
- Fanconi syndrome
- Rash
- Dizziness
- Headache
- Hepatomegaly
- Nausea
- Insomnia
- Arthralgia
- Vomiting
- Depression
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