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QUINOXALINE1
SynDRA canonical compound SYN0008969 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CDK1 |
|---|
| Mechanism of action | GSK-3 inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- GSK-3 inhibitor
- CDK1 INHIBITOR
- CDK5 INHIBITOR
- GSK3B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CDK2
- EIF2AK2
- ABL1
- PRKCA
- PDPK1
- PHKG2
- PIM1
- PIM2
- PIM3
- PKN2
- PLK1
- PLK2
- PLK3
- PLK4
- PRKAA2
- PRKACA
- PRKCB
- PDGFRA
- PRKCD
- PRKCE
- PRKCG
- PRKCH
- PRKCI
- PRKCQ
- PRKCZ
- PRKD1
- PRKD2
- PRKG1
- PRKX
- PTK2
- PTK2B
- PDGFRB
- PBK
- RAF1
- PASK
- MAPT
- MARK1
- MARK2
- MELK
- MERTK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CCNA2
- CCNB1
- CCNE1
- CDK5R1
- CP1A2
- CP2C9
- CP2CJ
- GEM
Cross-references
Synonyms
- NSC-693868
- 1H-Pyrazolo[3,4-b]quinoxalin-3-amine
- Cdk1/5 Inhibitor
- 3-Amino-1H-pyrazolo[3,4-b]quinoxaline
- 2H-pyrazolo[4,3-b]quinoxalin-3-amine
- 2H-PYRAZOLO[3,4-B]QUINOXALIN-3-AMINE
- NSC693868
- quinoxaline 1
- CDK1-5-inhibitor
- Tocris-1937
- K00033
- BDBM7534
- GTPL5947
- orb1704276
- SCHEMBL1394500
- SCHEMBL29447180
- CHEBI:92540
- DWHVZCLBMTZRQM-UHFFFAOYSA-N
- GLXC-03356
- HMS3229C18
- HMS3268M10
- HMS3412L20
- HMS3676L20
- 3-Aminopyrazolo[3,4-b]quinoxaline
- EX-A10888
- HSCI1_000152
- MFCD04038461
- AKOS006293899
- AKOS024456869
- pyrazolo[3,4-b]quinoxaline deriv. 1
- CCG-206825
- SDCCGSBI-0086738.P003
- NCGC00025317-01
- NCGC00025317-02
- MS-33219
- NCI60_033600
- DB-261134
- HY-103381
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