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PAXILLINE
SynDRA canonical compound SYN0008961 — structure-anchored drug synonym record
| Primary target(s) | KCNMA1 |
|---|
| Mechanism of action | Potassium channel blocker |
|---|
All known targets
Mechanisms of action (all sources)
- Potassium channel blocker
- NR1H3 AGONIST
- KCNMB4 BLOCKER (CHANNEL BLOCKER)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ATP2A3
- ATP2A2
- APOBEC3F
- MAPT
- TDP1
- TARDBP
- SMAD3
- PIN1
- OSBP2
- OSBP
- NPSR1
- KDM4A
- KMT2A
- IDH1
- HTT
- GMNN
- GLP1R
- EHMT2
- BAZ2B
- ATXN2
- TSG101
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- B2CL1
- BARD1
- BRCA1
- GEMI
- MCL1
- MDM2
- MDM4
- MRGPRX1
- NPY1R
- NPY2R
Drug classes
- Potassium Channel Blockers
Cross-references
Synonyms
- 4b-Hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one
- paxillin
- AC1L1IR1
- GTPL2309
- BDBM86263
- CTK7H1286
- ACNHBCIZLNNLRS-UHFFFAOYSA-N
- NCGC00168476-01
- CAS_57186-25-1
- hydroxy-(1-hydroxy-1-methyl-ethyl)-dimethyl-[ ]one
- 4b-Hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bh)-one #
- 3T9U9Z96L7
- NSC 658707
- RefChem:858745
- DTXCID801530123
- BRN 5317894
- MLS000028812
- SMR000058863
- PAXILINE
- UNII-3T9U9Z96L7
- (+)-paxilline
- Spectrum5_001975
- CBiol_001842
- BSPBio_001427
- KBioGR_000147
- KBioSS_000147
- SCHEMBL361232
- cid_105008
- orb1708933
- BDBM50854
- CHEBI:34907
- KBio2_000147
- KBio2_002715
- KBio2_005283
- KBio3_000293
- KBio3_000294
- MSK7233
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