MOFEZOLAC

SynDRA canonical compound SYN0008948 — structure-anchored drug synonym record

Clinical phase	Launched
Primary target(s)	PTGS1
Mechanism of action	cyclooxygenase inhibitor
Indication	osteoporosis \| rheumatoid arthritis
Disease area	orthopedics \| rheumatology

All known targets

PTGS1
PTGS2

Mechanisms of action (all sources)

PTGS1 INHIBITOR
cyclooxygenase inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

MYC

Drug classes

Analgesics
Analgesics, Non-Narcotic
Anti-Inflammatory Agents
Anti-Inflammatory Agents, Non-Steroidal
Antirheumatic Agents
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Peripheral Nervous System Agents
Sensory System Agents

Cross-references

PubChem CID: 4237
ChEMBL: CHEMBL259972
DrugBank: DB21153
ChEBI: CHEBI:31860
KEGG: D01718
RxNorm: 11469
PDB: 63X
Wikipedia: Mofezolac
LINCS BRD: BRD-K49372556

Synonyms

N-22
Mofezolaco
Mofezolacum
RVJ0BV3H3Y
(3,4-bis(4-methoxyphenyl)-5-isoxazolyl)acetic acid
DTXCID9026716
3,4-DMPIAA
N-22 compound
[3,4-bis(4-methoxyphenyl)-5-isoxazolyl]acetic acid
(3,4-di-(4-methoxyphenyl)-5-isoxazolyl)acetic acid
RefChem:159308
Disopain
2-(3,4-bis(4-methoxyphenyl)isoxazol-5-yl)acetic acid
Mofezolac [INN]
2-[3,4-bis(4-methoxyphenyl)-1,2-oxazol-5-yl]acetic acid
5-Isoxazoleacetic acid, 3,4-bis(4-methoxyphenyl)-
3,4-bis(p-Methoxyphenyl)-5-isoxazoleacetic acid
NCGC00167563-01
2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid
[3,4-bis(4-methoxyphenyl)-1,2-oxazol-5-yl]acetic acid
Mofezolacum [INN-Latin]
Mofezolaco [INN-Spanish]
CCRIS 4316
UNII-RVJ0BV3H3Y
BRN 5986171
Mofezolac?
DJEIHHYCDCTAAH-UHFFFAOYSA-N
Mofezolac (TN)
3,4-Bis(4-methoxyphenyl)-5-isoxazoleacetic acid
3,4-Bis((4-methoxyphenyl)-5-isooxazolyl)acetic acid
Acetic acid, 3,4-bis(4-methoxyphenyl)-5-isooxazolyl-
Mofezolac (JAN/INN)
MOFEZOLAC [JAN]
MOFEZOLAC [MI]
CBKinase1_012222
CBKinase1_024622
MOFEZOLAC [MART.]
MOFEZOLAC [WHO-DD]

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