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QUINETHAZONE
SynDRA canonical compound SYN0008930 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | SLC12A3 |
|---|
| Mechanism of action | Thiazide diuretic |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- SLC12A3 INHIBITOR
- Thiazide-sensitive sodium-chloride cotransporter inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA2
- ADORA1
- NR1I2
- NFE2L2
- MLNR
- MC4R
- MC3R
- MAOA
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HDAC6
- NPY1R
- NR3C1
- ESR1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SMPD1
- TBXA2R
- GHSR
- ERG
- ADORA2A
- CA3
- ADORA3
- ADRA1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Diuretics
- Membrane Transport Modulators
- Natriuretic Agents
- Sodium Chloride Symporter Inhibitors
- Thiazide diuretic
ATC classes
- C03B · LOW-CEILING DIURETICS, EXCL. THIAZIDES
Cross-references
Synonyms
- HYDROMOX
- HYDROMOX R
- quimethazin
- quinethazon
- quinethazonum
- Quinetazona
- NSC-759904
- Hydromox
- Quinethazone component of hydromox r
- Aquamox
- Chinetazone
- Chinethazone
- Chinethazonum
- Idrokin
- Quinethazon
- Quinethazonum
- Chinetazone[DCIT]
- CL 36010
- Hydromox (TN)
- Quinetazona [INN-Spanish]
- Quinethazone (aquamox)
- Quinethazonum [INN-Latin]
- Quinethazone (JAN/INN)
- Quinethazone [INN:BAN:JAN]
- Chinetazone [DCIT]
- QUINETHAZONE (1.5 G)
- NSC 759904
- CHEBI:8717
- 455E0S048W
- CCRIS 6098
- HSDB 3392
- EINECS 200-801-7
- BRN 0818554
- UNII-455E0S048W
- CAS-73-49-4
- NCGC00016313-01
- Quinethazone [USP:INN:BAN:JAN]
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