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ETONOGESTREL
SynDRA canonical compound SYN0008929 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | CYP2C19 | ESR1 | PGR |
| Mechanism of action | progesterone receptor agonist |
| Indication | contraceptive |
| Disease area | endocrinology |
All known targets
Mechanisms of action (all sources)
- PGR AGONIST
- PGR BINDER
- PGR MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AR
- ACHE
- OPRM1
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- OPRD1
- OPRK1
- PDE3A
- HTR1A
- PDE4A
- PDE4D
- PTGS1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR2A
- HRH3
- ADORA1
- HRH2
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB2
- CHRM1
- CHRM2
- CHRM3
- CNR1
- DRD1
- DRD2
- DRD3
- F2
- HDAC6
- HRH1
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Reproductive Control Agents
- Progestin
- Contraceptives, Oral, Hormonal
- Contraceptives, Oral, Synthetic
- Hormones
- Progestins
ATC classes
- G03A · HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- ELURYNG
- ENILLORING
- ETHINYL ESTRADIOL; ETONOGESTREL
- HALOETTE
- IMPLANON
- NEXPLANON
- NUVARING
- Nexplanon
- VERARING
- implanon
- 3-Oxodesogestrel
- ORG-3236
- Etonogestrel component of nuvaring
- Desogestrel related compound c
- Etonogestrelum
- Implanon
- Implanon (TN)
- NuvaRing (TN)
- Etonogestrel (USAN/INN)
- 3-Ketodesogestrel
- NUVARING COMPONENT ETONOGESTREL
- desogestrel related compound c (usp-rs)
- etonogestrel (usp-rs)
- desogestrel related compound c
- desogestrel impurity d (ep impurity)
- ORG 3236
- DESOGESTREL IMPURITY D
- nexplanon
- 3-Keto-desogestrel
- etonogestrelum
- DTXCID7026782
- CHEBI:50777
- 3-oxo desogestrel
- RefChem:56821
- G03AC08
- MFCD00867863
- Desogestrel EP Impurity D
- UNII-304GTH6RNH
Reported adverse events
- Migraine
- Vomiting
- Thrombophlebitis
- Erythema multiforme
- Erythema nodosum
- Hirsutism
- Rash
- Cerebral thrombosis
- Myocardial infarction
- Hypertension
- Pulmonary embolism
- Colitis
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