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ATALUREN
SynDRA canonical compound SYN0008871 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | DMD |
|---|
| Mechanism of action | Dystrophin stimulant |
|---|
| Indication | cystic fibrosis | duchenne muscular dystrophy (DMD) |
|---|
| Disease area | genetics | pulmonary |
|---|
All known targets
- DMD
- BLVRB
- RPS12
- RPS19
- RPS18
- RPS17
- RPS16
- RPS15A
- RPS15
- RPS14
- RPS13
- RPS11
Mechanisms of action (all sources)
- CFTR channel agonist
- Dystrophin stimulant
- RPSA MODULATOR
- RPS27 MODULATOR
- RPS6 MODULATOR
- RPS2 MODULATOR
- RPS3 MODULATOR
- RPS3A MODULATOR
- RPS4X MODULATOR
- RPS4Y1 MODULATOR
- RPS5 MODULATOR
- RPS7 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HDAC6
- ESR1
- MAOA
- NR1I2
- ACHE
- HTR2A
- KCNH2
- KDR
- MC3R
- NFE2L2
- OPRM1
- PDE3A
- PDE4A
- PDE4D
- PGR
- PTGS1
- SLC6A2
- SLC6A3
- SLC6A4
- HTR2B
- HRH3
- HTR1A
- ADORA1
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2C
- ADRB2
- AR
- CHRM1
- CHRM2
- CHRNA4
- DRD1
- DRD2
- DRD3
- F2
- HRH1
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- AHR
- ANDR
- ATAD5
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- ESRRA
- GLI3
- HDAC9
- HTT
- IP6K1
- RARA
ATC classes
- M09A · OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
Cross-references
Synonyms
- translarna
- PTC124
- Atalureno
- Translarna
- PTC-124
- 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid
- PTC 124
- 3-[5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
- PTC124 (Ataluren)
- UNII-K16AME9I3V
- Ataluren (PTC124)
- K16AME9I3V
- NCGC00168759-02
- AK-31904
- Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-
- DSSTox_CID_26776
- DSSTox_RID_81895
- DSSTox_GSID_46776
- Benzoic acid, 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)-
- CAS-775304-57-9
- Ataluren [USAN:INN]
- Translarna (TN)
- PTC124,Ataluren
- Ataluren(ptc124)
- DTXCID3026776
- atalurenum
- RefChem:560297
- M09AX03
- MFCD09864996
- Ataluren [USAN]
- Ataluren (Standard)
- Ataluren; PTC124
- ATALUREN [INN]
- ATALUREN [MI]
- PTC124 (Ataluren)?
- ATALUREN [WHO-DD]
- SCHEMBL60614
- Ataluren (JAN/USAN/INN)
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