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TILARGININE
SynDRA canonical compound SYN0008789 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | NOS1 | NOS2 |
|---|
| Mechanism of action | nitric oxide synthase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- NOS1 INHIBITOR
- Nitric oxide synthase inhibitor
- NOS2 INHIBITOR
- NOS3 INHIBITOR
- NOS3 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ARSA
- GMNN
- TDP1
- SLCO1B3
- SLCO1B1
- PTGES
- KCNH2
- HDAC6
- EHMT2
- CBX1
- DDAH1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Tilarginina
- Ng-methylarginine
- .omega.-n-methylarginine
- Ng-monomethyl-l-arginine
- Omega-n-methylarginine
- Omega-n-methylated arginine
- L-NMMA
- targinine
- N-Methylarginine
- NG-Methylarginine
- tilarginina
- omega-N-Monomethylarginine
- N(G)-Methylarginine
- L-NG-Monomethyl Arginine
- tilargininum
- N5-(Methylamidino)-L-ornithine
- (2S)-2-amino-5-[(N'-methylcarbamimidoyl)amino]pentanoic acid
- (2S)-2-amino-5-((N'-methylcarbamimidoyl)amino)pentanoic acid
- RefChem:1092346
- (2S)-2-azaniumyl-5-((N'-methylcarbamimidoyl)amino)pentanoate
- Targinine
- L-Monomethylarginine
- N-Monomethyl-L-arginine
- omega-N-METHYLARGININE
- N(G)-monomethyl L-arginine
- Nomega-Monomethyl-L-arginine Acetate
- Tilarginine [INN]
- Ngamma-Monomethyl-L-arginine
- L-Targinine
- N(omega)-methyl-L-arginine
- N-omega-monomethyl-L-arginine
- NG-Monomethyl-L-arginine acetate
- N(5)-(methylamidino)-L-ornithine
- nomega-monomethyl-l-arginine
- N(5)-(N-methylcarbamimidoyl)-L-ornithine
- (2S)-2-amino-5-(N'-methylcarbamimidamido)pentanoic acid
- N(5)-[imino(methylamino)methyl]-L-ornithine
- (S)-2-Amino-5-(3-methylguanidino)pentanoic acid
- L-Arginine, 2
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