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LUMIRACOXIB
SynDRA canonical compound SYN0008575 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PPARG
- NR1I3
- ABCB11
- NR3C1
- HTR2C
- HTR3A
- KCNH2
- KDR
- MAOA
- MC3R
- MLNR
- NR1H2
- NR1H3
- NR1H4
- NR1I2
- OPRD1
- HTR2A
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARA
- RARA
- RARB
- RARG
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HTR2B
- HTR1A
- ACHE
- HRH3
- ADORA1
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- joicela
- prexige
- COX-189
- Prexige
- Joicela
- Novartis brand of lumiracoxib
- COX189
- Lumiracoxib [USAN:INN]
- Prexige (Novartis)
- Prexige (TN)
- Lumiracoxib (USAN/INN)
- 2-((2-Chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid
- 2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid
- 2-(2-((2-chloro-6-fluoro-phenyl)amino)-5-methyl-phenyl)acetic acid
- 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid
- COX 189
- lumiracoxibum
- V91T9204HU
- DTXCID4028961
- CHEBI:73044
- RefChem:800128
- M01AH06
- CGS-35189
- Prexige;COX 189
- MFCD07186254
- s2903
- NCGC00181795-01
- CAS-220991-20-8
- 4llz
- 4oty
- LUR
- Prexige, Lumiracoxib
- Lumiracoxib (Standard)
- LUMIRACOXIB [MI]
- LUMIRACOXIB [INN]
- LUMIRACOXIB [USAN]
- Lumiracoxib (COX-189)
- SCHEMBL4479
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