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RALTEGRAVIR
SynDRA canonical compound SYN0008539 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Mechanism of action | HIV integrase inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
- HIV integrase INHIBITOR
- HIV IN MODULATOR
- pol INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- SCN5A
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- POLB
- PTGS1
- SLC6A2
- ADORA3
- SLC6A3
- SLC6A4
- TBXA2R
- UGT1A1
- UGT1A4
- UGT1A6
- UGT1A9
- KDR
- KCNH2
- HTR2B
- HTR1A
- ADRA1A
- ADRA2A
- AR
- CACNA1C
- CHRM1
- CHRM2
- CYP1A2
- CYP2C9
- CYP2D6
- CYP3A4
- DRD1
- ESR1
- F2
- HDAC6
- HRH3
- UGT2B7
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- HIV Integrase Inhibitors
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Integrase Inhibitors
- Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- DUTREBIS
- ISENTRESS
- ISENTRESS HD
- Isentress
- RALTEGRAVIR POTASSIUM
- MK0518
- isentress
- raltegravir potassium
- MK-0518
- L-000900612
- L000900612
- RGV
- Isentress(TM)
- K-0518
- Raltegravir (INN)
- N-(2-(4-(4-fluorobenzylcarbamoyl)
- RAL
- MK 0518
- raltegravirum
- CHEBI:82960
- DTXCID5028586
- RefChem:55964
- J05AX08
- Raltegravir (MK-0518)
- MFCD10698872
- C20H21FN6O5
- NCGC00184997-01
- RALTEGRAVIR [INN]
- CAS-518048-05-0
- Raltegravir [USAN:INN]
- UNII-22VKV8053U
- Raltegravir?
- HSDB 8124
- RLT
- RALTEGRAVIR [MI]
- Raltegravir(MK-0518)
- Raltegravir; MK-0518
- Epitope ID:231726
Reported adverse events
- Myopathy
- Rash
- Stevens-Johnson syndrome
- Fatigue
- Headache
- Insomnia
- Nausea
- Infestation
- Dizziness
- Hepatitis
- Asthenia
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