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ENOXIMONE
SynDRA canonical compound SYN0008514 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PDE3A |
|---|
| Mechanism of action | phosphodiesterase inhibitor |
|---|
| Indication | congestive heart failure |
|---|
| Disease area | cardiology |
|---|
All known targets
- PDE3A
- PDE3B
- PDE4A
- PDE4B
- PDE4C
- PDE4D
Mechanisms of action (all sources)
- PDE3A INHIBITOR
- Phosphodiesterase 3 inhibitor
- PDE3B INHIBITOR
- phosphodiesterase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- ADORA1
- MPHOSPH8
- MLNR
- MC4R
- MC3R
- MBNL1
- MAOA
- KCNH2
- KAT2A
- HRH1
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH3
- NFKB1
- NPSR1
- NPY1R
- NR1I2
- TSHR
- TBXA2R
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- RGS4
- PTGS2
- PMP22
- PLK1
- PGR
- OPRM1
- OPRK1
- OPRD1
- NR3C1
- HRH2
- HPGD
- ADORA2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cardiotonic Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Phosphodiesterase 3 Inhibitors
- Phosphodiesterase Inhibitors
- Protective Agents
- Vasodilator Agents
ATC classes
- C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
Cross-references
Synonyms
- fenoximone
- Enoximona
- MDL 17,043
- MDL-17043
- Perfan
- Fenoximone
- Enoximonum [Latin]
- Enoximona [Spanish]
- MDL-17,043
- UNII-C7Z4ITI7L7
- RMI-17043
- 4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one
- C7Z4ITI7L7
- 4-Methyl-5-(p-(methylthio)benzoyl)-4-imidazolin-2-one
- CHEMBL249856
- 2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-
- NCGC00015400-02
- Enoximonum
- 1,3-Dihydro-4-methyl-5-[4-methylthiobenzoyl]-2H-imidazol-2-one
- DSSTox_RID_80702
- DSSTox_CID_25147
- DSSTox_GSID_45147
- Perfane
- E 1279
- Perfan (TN)
- Enoximone (USAN/INN)
- Enoximone [USAN:BAN:INN]
- 1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one
- 1,3-Dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-one
- 2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-
- 4-methyl-5-[4-(methylsulfanyl)benzoyl]-2,3-dihydro-1H-imidazol-2-one
- SMR000857318
- CAS-77671-31-9
- Enoximone [USAN:INN:BAN]
- Enoximone, solid
- ENOXIMONE [INN]
- ENOXIMONE [JAN]
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