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ESZOPICLONE
SynDRA canonical compound SYN0008487 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABRQ |
|---|
| Mechanism of action | GABA receptor agonist |
|---|
All known targets
- GABRA1
- GABRA3
- GABRA4
- GABRA5
- GABRB2
- GABRA2
- GABRG3
- GABRG2
- GABRG1
- GABRQ
- GABRP
- GABRB3
Mechanisms of action (all sources)
- GABA receptor agonist
- GABRA1 POSITIVE ALLOSTERIC MODULATOR
- GABRB2 POSITIVE ALLOSTERIC MODULATOR
- GABRG2 POSITIVE ALLOSTERIC MODULATOR
- GABRB3 POSITIVE ALLOSTERIC MODULATOR
- GABRA4 POSITIVE ALLOSTERIC MODULATOR
- GABRG3 POSITIVE ALLOSTERIC MODULATOR
- GABRQ POSITIVE ALLOSTERIC MODULATOR
- GABRA3 POSITIVE ALLOSTERIC MODULATOR
- GABRP POSITIVE ALLOSTERIC MODULATOR
- GABRD POSITIVE ALLOSTERIC MODULATOR
- GABRG1 POSITIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Central Nervous System Agents
- Central Nervous System Depressants
- Hypnotics and Sedatives
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
Cross-references
Synonyms
- LUNESTA
- Lunesta
- esopiclone
- lunesta
- Eszopiclona
- Zopiclone s-form
- Estorra
- Eszopiclon
- (S)-ZOPICLONE
- GSK-1755165
- Eszopiclone civ
- Esopiclone
- Lunivia
- Estorra (TN)
- Eszopiclone [USAN:INN]
- KS-1055
- SEP-0227018
- SEP-0227108
- SEP-190
- SEP-225441
- Eszopiclone (JAN/USAN/INN)
- (S)-Zopiclone
- (plus)-Zopiclone
- eszopiclone civ (usp-rs)
- Zopiclone s-
- UZX80K71OE
- eszopiclone (usp monograph)
- (+)-Zopiclone
- eszopiclona
- CHEBI:53760
- DTXCID6026086
- eszopiclonum
- RefChem:56355
- N05CF04
- NCGC00159515-02
- C17H17ClN6O3
- (S)-Eszopiclone
Reported adverse events
- Anxiety
- Depression
- Dizziness
- Dyspepsia
- Hallucination
- Headache
- Nausea
- Nervousness
- Pruritus
- Rash
- Somnolence
- Vomiting
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