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ELETRIPTAN
SynDRA canonical compound SYN0008338 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR1A | HTR1B | HTR1D | HTR1E | HTR1F | HTR2B | HTR7 |
|---|
| Mechanism of action | serotonin receptor agonist |
|---|
| Indication | migraine headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR1B
- HTR1D
- HTR1F
- HTR1A
- HTR1E
- HTR2B
- HTR7
Mechanisms of action (all sources)
- HTR1F AGONIST
- Serotonin 1f (5-HT1f) receptor agonist
- HTR1B AGONIST
- Serotonin 1b (5-HT1b) receptor agonist
- HTR1D AGONIST
- Serotonin 1d (5-HT1d) receptor agonist
- serotonin receptor agonist
- HTR1B MODULATOR
- HTR1D MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH3
- ADRA2A
- CHRM2
- OPRM1
- SLC6A2
- PDE4A
- PGR
- PTGS1
- SLC47A1
- SLC47A2
- SLC6A4
- SLC6A3
- SLCO1B1
- SLCO1B3
- SLCO2B1
- TBXA2R
- PDE3A
- ABCB1
- MAOA
- ACHE
- HDAC6
- GLS
- F2
- ESR1
- DRD3
- DRD1
- CYP3A4
- CYP2J2
- CHRM1
- AR
- ADRA1A
- ADORA3
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- GLI3
- NR1I2
- NNMT
- KCNH2
- JUN
- HNMT
- GNMT
- GAMT
- 5HT1E
- CP3A7
- CP3A4
- CP2D6
- CP2C9
- COMT
- 5HT2A
- PNMT
Drug classes
- Neurotransmitter Agents
- Serotonin Agents
- Serotonin Receptor Agonists
- Serotonin 1b Receptor Agonists
- Serotonin 1d Receptor Agonists
- Serotonin-1b and Serotonin-1d Receptor Agonist
ATC classes
- N02C · ANTIMIGRAINE PREPARATIONS
Cross-references
Synonyms
- ELETRIPTAN HYDROBROMIDE
- RELPAX
- Relpax
- eletriptan hydrobromide
- UK 116044-04
- UK-116,044
- relpax
- UK-116,044-04 FREE BASE
- UK-116044
- UK-116044-04 FREE BASE
- Eletriptanum
- UK116044
- Eletriptan (INN)
- Eletriptan [INN:BAN]
- Relpax (TN)
- UK-116044-04
- eletriptanum
- CHEBI:50922
- DTXCID7026861
- RefChem:57394
- N02CC06
- UK-166044
- UK-166,044
- NCGC00181130-01
- ELETRIPTAN [INN]
- CAS-143322-58-1
- UNII-22QOO9B8KI
- MFCD00943792
- Eletriptan, Free Base
- ELETRIPTAN [MI]
- ELETRIPTAN [VANDF]
- GTPL40
- ELETRIPTAN [WHO-DD]
- SCHEMBL26719
- orb1710738
- SCHEMBL29414096
- HY-A0039
- Tox21_112737
Reported adverse events
- Asthenia
- Dizziness
- Dry mouth
- Dyspepsia
- Dysphagia
- Headache
- Nausea
- Somnolence
- Arrhythmia
- Flushing
- Hypersensitivity
- Serotonin syndrome
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