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PYRROLIDINE DITHIOCARBAMATE
SynDRA canonical compound SYN0008325 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HSD11B1 |
|---|
| Mechanism of action | NFKB pathway inhibitor |
|---|
All known targets
- HSD11B1
- RELA
- NFKB1
- NFKB2
- REL
- RELB
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA9
- CA1
- CA12
- CA2
- PLK1
- KDM4E
- LMNA
- MAPK1
- MAPT
- MPHOSPH8
- MTOR
- NFE2L2
- NPSR1
- ALDH1A1
- PMP22
- HSD17B10
- POLI
- RGS4
- SMN1
- TDP1
- THPO
- TP53
- KCNH2
- HIF1A
- HPGD
- ALOX12
- ALOX15
- ALOX15B
- APOBEC3F
- APOBEC3G
- APP
- ATAD5
- CBX1
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- EHMT2
- GMNN
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- CP1A2
- CP2C9
- CP2CJ
- ESRRA
- GLSK
- NPR1
- NTM1A
- PHGDH
- TPO
Drug classes
Cross-references
Synonyms
- Pyrrolidine-1-carbodithioic acid
- Pyrrolidine dithiocarbamic acid
- Pyrrolidinedithiocarbamate
- 1-Pyrrolidinecarbodithioic acid
- PDTC
- apdc
- Tetramethylenedithiocarbamic acid
- Pyrrolidine-N-carbodithioic acid
- Ammonium pyrrolidine dithiocarbamate
- 1-Pyrrolidinecarbodithioic acid, ammonium salt
- CHEBI:78782
- Ammonium 1-pyrrolidinecarbodithioate
- C5H9NS2
- NSC298194
- Pyrrolidine-N-dithiocarbamic acid ammonium salt
- ammonium tetramethylene dithiocarbamate
- NCIOpen2_000025
- pyrrolidine-dithiocarbamate
- Pyrrolidinecarbodithioic acid
- RefChem:930404
- DTXCID10102928
- RG3HRQ45HY
- 1-Pyrrolidinedithiocarbamic acid
- 1-PYRROLIDINEDITHIOCARBOXYLIC ACID
- UNII-RG3HRQ45HY
- Lopac0_001033
- SCHEMBL214633
- SCHEMBL322100
- 1-Pyrrolidinecarbodithioic acid #
- PDTC & Z-100
- VSWDORGPIHIGNW-UHFFFAOYSA-N
- HMS1787J02
- EBC-06135
- PDSP1_000811
- PDSP1_000812
- PDSP2_000798
- PDSP2_000799
- STL146643
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