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ESCITALOPRAM
SynDRA canonical compound SYN0008318 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Selective serotonin reuptake inhibitor |
|---|
| Indication | depression | generalized anxiety disorder (GAD) |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A4
- ADRA1A
- CHRM1
- HRH1
- SLC6A2
- CYP2C19
- HTR2C
- NET
- SLC6A3
- Slc6a3
- Slc6a4
Mechanisms of action (all sources)
- Selective serotonin reuptake inhibitor
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- selective serotonin reuptake inhibitor (SSRI)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR6
- KCNH2
- OPRM1
- MLNR
- MC3R
- MAPK1
- MAOA
- LMNA
- KDM4A
- ABL1
- NPY1R
- HTR3A
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HDAC6
- NFKB1
- NR1I2
- GMNN
- SAMHD1
- TRIM24
- TDP1
- TBXA2R
- SLCO1B3
- SLCO1B1
- SLC29A1
- PTGS2
- NR3C1
- POLK
- PGR
- PDE4D
- PDE3A
- OPRK1
- OPRD1
- GSK3B
- GLP1R
- ADORA1
- CBX1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- CP2C9
- CP2CJ
- CP2D6
- CP3A7
- GLI3
- KSYK
- NTM1A
- NTMT1
- SYK
Drug classes
- Serotonin Uptake Inhibitors
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Selective Serotonin Reuptake Inhibitors
- Serotonin Agents
- Serotonin Reuptake Inhibitor
ATC classes
Cross-references
Synonyms
- ESCITALOPRAM OXALATE
- LEXAPRO
- Lexapro
- (+)-(S)-Citalopram
- (+)-Citalopram
- (S)-Citalopram
- S-(+)-Citalopram
- seroplex
- escitalopram oxalate
- ESERTIA
- ESITOL
- (S)-(+)-CITALOPRAM
- (S)-CITALOPRAM
- Cipralex
- Escitalopram oxalate
- LU-26-054
- S-(+)-CITALOPRAM
- SEROPLEX
- Esertia
- Escitalopram [INN]
- Cipralex (TN)
- Escitalopram (INN)
- Esertia (TN)
- Lexapro (TN)
- S(+)-Citalopram
- escitalopram (ep monograph)
- 4O4S742ANY
- Esitol
- Seroplex
- escitalopramum
- CHEBI:36791
- RefChem:5803
- DTXCID4028414
- N06AB10
- Escitalopram [INN:BAN]
- UNII-4O4S742ANY
- Escitalopram CRS
Reported adverse events
- Suicide
- Serotonin syndrome
- Dizziness
- Fatigue
- Insomnia
- Seizure
- Parkinsonism
- Priapism
- Anorgasmia
- Constipation
- Somnolence
- Nausea
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