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COUMAPHOS
SynDRA canonical compound SYN0008243 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Mechanism of action | cholinesterase inhibitor |
|---|
All known targets
- CA1
- CA12
- CA13
- CA14
- CA3
- CA4
- CA5A
- CA5B
- CA6
- CA7
- CA9
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AHR
- KDM4A
- TDP1
- TARDBP
- SLCO1B3
- SLCO1B1
- RXRA
- NFE2L2
- KDM4E
- HPGD
- ALDH1A1
- HDAC6
- GMNN
- GLP1R
- ESR1
- CYP3A4
- CBX1
- APOBEC3F
- THRB
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- ANDR
- RARA
- PRIO
- PRGR
- NSD2
- NR1I2
- NR1H4
- NF2L2
- KCNH2
- IP6K1
- HDAC9
- GLI3
- ESRRA
- DRD2
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- TSHR
Drug classes
- Anthelmintics
- Anti-Infective Agents
- Antinematodal Agents
- Antiparasitic Agents
- Cholinergic Agents
- Cholinesterase Inhibitors
- Enzyme Inhibitors
- Insecticides
- Neurotransmitter Agents
- Pesticides
Cross-references
Synonyms
- coumafos
- meldane
- NSC-8944
- BAYER-21199
- Coumafos
- Cumafos
- coumophos
- Asuntol
- Asunthol
- Meldane
- Muscatox
- Resitox
- Baymix
- Azunthol
- Agridip
- Meldone
- Suntol
- CO-Ral
- Baymix 50
- Diolice
- Negashunt
- Umbethion
- Bayer 21/199
- Cumafosum
- Negasunt
- NCI-C08662
- Coumafosum
- Resistox
- 3-Chloro-4-methyl-7-coumarinyl diethyl phosphorothioate
- BAY 21/199
- ENT 17,957
- O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate
- OMS 485
- 3-Chloro-7-diethoxyphosphinothioyloxy-4-methylcoumarin
- Diethyl 3-chloro-4-methylumbelliferyl thionophosphate
- NSC 8944
- L08SZ5Z5JC
- O,O-Diethyl O-(3-chloro-4-methylcoumarinyl-7) thiophosphate
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