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TRIAMCINOLONE ACETONIDE
SynDRA canonical compound SYN0008016 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | Glucocorticoid receptor agonist |
|---|
| Indication | corticosteroid-responsive dermatoses |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- ANXA1
- CYP3A5
- CYP3A7
- PGR
- SERPINA6
Mechanisms of action (all sources)
- NR3C1 AGONIST
- glucocorticoid receptor agonist, immunosuppressant
- NR3C1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- NR1I2
- ACHE
- IDH1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- HTR6
- MMP9
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HIF1A
- HDAC6
- MMP1
- NFE2L2
- GHSR
- PTPRC
- TBXAS1
- TBXA2R
- TARDBP
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- ANDR
- CFTR
- CP2D6
- CP3A4
- GLI3
- HSPB1
- KSYK
- LRC26
- MRP1
- NSD2
- PRGR
- SYK
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Glucocorticoids
- Hormones
- Immunologic Factors
- Immunosuppressive Agents
- immunosuppressant
- Enzyme Inhibitors
- anti-inflammatory agent
ATC classes
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- R03B · OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- S01B · ANTIINFLAMMATORY AGENTS
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- D07A · CORTICOSTEROIDS, PLAIN
- A01A · STOMATOLOGICAL PREPARATIONS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
- CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Cross-references
Synonyms
- ALLERNAZE
- ARISTOCORT
- ARISTOCORT A
- ARISTOGEL
- AZMACORT
- AllerNaze
- FLUTEX
- KENALOG
- KENALOG IN ORABASE
- KENALOG-10
- KENALOG-40
- KENALOG-80
- nasacort
- aristicort
- allernaze
- Kenacourt
- FX-006
- FX006
- NSC-21916
- Adcortyl
- Adcortyl in orabase
- Allernaze
- Aristocort
- Aristocort a
- Aristogel
- Audicort
- Aureocort
- Azmacort
- Extracort
- Flutex
- Ftorocort
- Gppe ear dps cap
- Gppe ear oint
- Kenacort-a
- Kenalog in orabase
- Kenalog-10
- Kenalog-40
- Kenalog-80
Reported adverse events
- Perioral dermatitis
- Acne
- Arachnoiditis
- Bradycardia
- Exophthalmos
- Spinal cord infarction
- Hypertrichosis
- Folliculitis
- Skin atrophy
- Cough
- Anaphylactoid reaction
- Dyspepsia
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