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BETAMETHASONE VALERATE
SynDRA canonical compound SYN0007987 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
| Indication | corticosteroid-responsive dermatoses |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- ANXA1
- Nr3c1
- HRH1
- CHRM1
- CHRM3
- CHRM4
- CHRM5
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PGR
- ADORA1
- OPRD1
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- OPRK1
- ADORA2A
- OPRM1
- PDE3A
- PDE4D
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- HRH3
- HRH2
- HRH1
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- ESRRA
- GNRHR
- NR1I2
- NSD2
- PRGR
- RARA
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Asthmatic Agents
- Anti-Inflammatory Agents
- Glucocorticoids
- Hormones
- Respiratory System Agents
- anti-inflammatory agent
ATC classes
- D07A · CORTICOSTEROIDS, PLAIN
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- S02B · CORTICOSTEROIDS
- S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- R03B · OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
- S01B · ANTIINFLAMMATORY AGENTS
- A07E · INTESTINAL ANTIINFLAMMATORY AGENTS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
Cross-references
Synonyms
- BETA-VAL
- BETADERM
- BETATREX
- DERMABET
- LUXIQ
- Luxiq
- VALISONE
- VALNAC
- bextasol
- celeston valerate
- valisone
- bedermin
- Betamethasone 17-valerate
- Betamethasone (as valerate)
- Betamethasoni valeras
- Rinderon v
- Stanoval
- Tokuderm
- NSC-755912
- Audavate
- Audavate rd
- Beta-val
- Betacap
- Betaderm
- Betameth val in coal tar
- Betatrex
- Betesil
- Betnovate rd
- Betnovate-c
- Betnovate-n
- Bettamousse
- Bextasol
- Dermabet
- Fucibet
- Valisone
- Valnac
- Xemacort
Reported adverse events
- Cardiac arrest
- Cushing's syndrome
- Hypersensitivity
- Skin atrophy
- Erythema
- Rash
- Acne
- Perioral dermatitis
- Pruritus
- Anaphylactoid reaction
- Arachnoiditis
- Bradycardia
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