IDEBENONE

SynDRA canonical compound SYN0007943 — structure-anchored drug synonym record

Clinical phase	Launched
Mechanism of action	calcium channel modulator
Indication	Alzheimer's disease \| Friedreich's ataxia \| Leber hereditary optic neuropathy (LHON)
Disease area	neurology/psychiatry \| ophthalmology

All known targets

CYP2C19
CYP2C9
CYP2D6
CYP3A4
Sirt2

Mechanisms of action (all sources)

calcium channel modulator

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

Drug classes

Antioxidants
Protective Agents

ATC classes

N06B · PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS

Cross-references

PubChem CID: 3686
ChEMBL: CHEMBL252556
DrugBank: DB09081
ChEBI: CHEBI:31687
KEGG: D01750
RxNorm: 51296
Wikipedia: Idebenone
TTD: D0MM8N
LINCS BRD: BRD-K37516142

Synonyms

hydroxydecyl ubiquinone
CV 2619
daruma
raxone
Idebenona
Hydroxydecyl ubiquinone
Oristar hdu
Sovrima
NSC-759228
Raxone
Idebenonum
CV-2619
Idebenonum [Latin]
Idebenona [Spanish]
Idebenone [INN:JAN]
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
UNII-HB6PN45W4J
BRN 2001459
6-(10-Hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone
HB6PN45W4J
2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone
CHEBI:31687
JGPMMRGNQUBGND-UHFFFAOYSA-N
2,5-Cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-
NCGC00160514-01
AK161748
NSC 759228
2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone
DTXCID8020678
2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone
noben
6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone
RefChem:789668
N06BX13
MFCD00274552
5,6-DIMETHOXY-2-(10-HYDROXYDECYL)-3-METHYL-1,4-BENZOQUINONE
2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylbenzo-1,4-quinone

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