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FENDILINE
SynDRA canonical compound SYN0007917 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HTR2B |
|---|
| Mechanism of action | calcium channel blocker |
|---|
All known targets
- HTR2B
- CALM
- CASR
- SMPD1
- luxR
Mechanisms of action (all sources)
- calcium channel blocker
- HTR2B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD3
- SLC6A3
- KCNH2
- CHRM2
- ADRA2A
- ESR1
- OPRM1
- DRD1
- SLC6A2
- SLC6A4
- PGR
- ABCC2
- PDE4A
- NPSR1
- MAOA
- KDR
- PDE3A
- PTGS1
- PIN1
- HTT
- SAMHD1
- SLCO1B1
- SLCO1B3
- SMAD3
- SMN1
- STING1
- TBXA2R
- TDP1
- IDH1
- HRH3
- HTR6
- ATXN2
- ADORA3
- ADRA1A
- ALDH1A1
- ALOX12
- ALOX15
- ALOX15B
- APOBEC3F
- AR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- MDR1
- KCNJ1
- KSYK
- M4K2
- MCHR1
- MDM2
- MDM4
- MLP3A
- ACM4
- NLRP1
- NPBW1
- NR1I2
- NSD2
- PRGR
- SYK
- JUN
- IFNG
- GLI3
- GEMI
- ESRRA
- ESR2
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP19A
- CASP7
- CASP3
- CASP1
- ANDR
- ADRB2
- TSHR
Drug classes
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Membrane Transport Modulators
ATC classes
- C08E · NON-SELECTIVE CALCIUM CHANNEL BLOCKERS
Cross-references
Synonyms
- fendiline hydrochloride
- fendilin
- (+/-)-Fendiline
- phendilin
- fendiline HCl
- Fendilina
- Fendilin
- Fendilinum
- Fendilinum [INN-Latin]
- Fendilina [INN-Spanish]
- Fendiline [INN]
- EINECS 235-915-6
- CHEMBL254832
- Fendiline (INN)
- Benzenepropanamine, gamma-phenyl-N-(1-phenylethyl)-
- Benzenepropanamine, .gamma.-phenyl-N-(1-phenylethyl)-
- 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine
- Phendilin
- Senzit
- NCGC00018223-06
- SPBio_001131
- Spectrum_000443
- AC1L1FPB
- Spectrum5_001302
- Spectrum2_001006
- Prestwick1_000270
- Spectrum4_000417
- Prestwick3_000270
- Spectrum3_001436
- Prestwick2_000270
- Phendilin; dl-Fendiline
- S253D559A8
- N-(3,3-Diphenylpropyl)-.alpha.-methylbenzylamine
- UNII-S253D559A8
- FENDILINE [MI]
- Prestwick0_000270
- FENDILINE [WHO-DD]
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