← SynDRA

DIPHENYLPYRALINE

SynDRA canonical compound SYN0007916 — structure-anchored drug synonym record

All known targets

• HRH1
• SLC6A3
• CHRM1
• CYP2D6
• Slc6a3

Mechanisms of action (all sources)

• Dopamine uptake inhibitor
• HRH1 ANTAGONIST
• Histamine H1 receptor antagonist
• dopamine reuptake inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• DRD1
• ADRA2A
• CHRM2
• OPRM1
• SLC6A2
• KCNH2
• DRD3
• PGR
• MAOA
• MAPK1
• PDE3A
• PDE4A
• ACHE
• PTGS1
• SAMHD1
• SLC6A4
• SLCO1B1
• SLCO1B3
• SMPD1
• KDR
• HTR1A
• HTR2B
• ADORA3
• HRH3
• HDAC6
• GALC
• F2
• ESR1
• EHMT2
• CYP3A4
• CYP2C9
• CYP2C19
• CYP1A2
• AR
• ADRA1A
• TBXA2R

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• 5HT2A
• ACM1
• ACM4
• ACM5
• CP2D6
• CP3A7
• S12A5
• SC6A3

ATC classes

• R06A · ANTIHISTAMINES FOR SYSTEMIC USE

Cross-references

• PubChem CID: 3103
• ChEMBL: CHEMBL1492
• DrugBank: DB01146
• ChEBI: CHEBI:59788
• KEGG: D01172
• RxNorm: 23386
• Wikipedia: Diphenylpyraline
• TTD: D0W6DY
• LINCS BRD: BRD-K22936972

Synonyms

• HISPRIL
• hispril
• diphenylpyraline maleate
• diphenpyraline
• diphenylpyrilene
• diphenylpyraline hydrochloride
• diphenylpyraline HCl
• Difenilpiralina
• Allergen
• Belfene
• Dafen
• Dayfen
• Diafen
• Diphenylpyralamine
• Diphenylpyralinum
• Diphenylpyrilene
• Hispril
• Histryl
• Histyn
• Hystryl
• Lergobine
• Lyssipoll
• Mepiben
• Neargal
• AN 1041
• Difenilpiralina [INN-Spanish]
• Diphenylpyraline (INN)
• Diphenylpyraline [INN:BAN]
• N-Methylpiperidyl-(4)-benzhydrylaether salzsauren salze
• N-Methylpiperidyl-(4)-benzhydrylaether salzsauren salze [German]
• 1-Methyl-4-piperidyl benzhydryl ether
• 1-methyl-4-hydroxypiperidine benzhydryl ether
• 4-(Benzhydryloxy)-1-methylpiperidine
• 4-(Diphenylmethoxy)-1-methylpiperidine
• 4-(benzhydryloxy)-N-methylpiperidine
• 4-DIPHENYLMETHOXY-1-METHYLPIPERIDINE
• 4-[(diphenylmethyl)oxy]-1-methylpiperidine
• 4-benzhydryloxy-1-methylpiperidine