CLOPERASTINE

SynDRA canonical compound SYN0007909 — structure-anchored drug synonym record

Clinical phase	Launched
Mechanism of action	antitussive
Indication	cough suppressant
Disease area	pulmonary

All known targets

KCNH2
SLC22A1

Mechanisms of action (all sources)

potassium channel antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ACM1
ACM4
ACM5
CP2CJ
CP2D6
CP3A4
CP3A7
DRD2
IL1B
JUN
MDR1
NSD2
RARA

Drug classes

antitussive

ATC classes

R05D · COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS

Cross-references

PubChem CID: 2805
ChEMBL: CHEMBL415087
DrugBank: DB09002
ChEBI: CHEBI:31419
KEGG: D01569
RxNorm: 2104180
Wikipedia: Cloperastine
TTD: D0O8IS
LINCS BRD: BRD-A80908310

Synonyms

hustazol
cloperastine hydrochloride
cloperastine fendizoate
cloperastine HCl
Cloperastina
HT-11
NSC-758635
Cloperastine hydrochloride
Seki
Cloperastine HCl
Cloperastina cloridrato [Italian]
EINECS 239-067-8
1-(2-((4-Chlorophenyl)(phenyl)methoxy)ethyl)piperidine hydrochloride
2-Piperidinoethyl p-chlorobenzhydryl ether hydrochloride
1-(2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine hydrochloride
1-(2-(p-Cloro-alpha-fenilbenzilossi)etil)piperidina cloridrato [Italian]
DSSTox_RID_80863
DSSTox_CID_25413
DSSTox_GSID_45413
Q-200881
4-Chlorobenzhydryl 2-(1-Piperidyl)ethyl Ether Hydrochloride
Cloperastinum
1-(2-((4-chlorophenyl)(phenyl)methoxy)ethyl)piperidine
HT 11
NSC 758635
1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine
1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine
RefChem:127073
1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine
DTXCID4027999
R05DB21
Cloperastine [INN]
1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine
EINECS 223-042-3
Piperidine, 1-[2-[(4-chlorophenyl)phenylmethoxy]ethyl]-
Cloperastine (hydrochloride)
Cloperastine (INN)
Piperidine, 1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)-

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