← SynDRA
ATORVASTATIN
SynDRA canonical compound SYN0007875 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HMGCR |
|---|
| Mechanism of action | HMGCR inhibitor |
|---|
| Indication | heart attack | stroke |
|---|
| Disease area | cardiology | neurology/psychiatry |
|---|
All known targets
- HMGCR
- DPP4
- ABCG2
- AHR
- CYP3A4
- CYP3A5
- FASLG
- HDAC1
- HDAC2
- HDAC6
- Hmgcr
- NR1I3
Mechanisms of action (all sources)
- HMGCR INHIBITOR
- HMG-CoA reductase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLCO1B1
- NR1I2
- NR1H4
- ESR1
- RHOC
- SLCO2B1
- SLCO1B3
- ABCB1
- MC3R
- MC4R
- MC5R
- MLNR
- MMP1
- MMP9
- NPY1R
- NPY2R
- NR1H2
- NR1H3
- NR3C1
- MAPK3
- MAPK1
- MAPK14
- OPRD1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- NTSR1
- PDE3A
- OPRK1
- OPRM1
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CASP3
- CASP7
- CP19A
- CP3A4
- CP3A7
- ESRRA
- GCR
- GPR151
- KSYK
- NF2L2
- NSD2
- NTM1A
- NTMT1
- PPARG
- SYK
Drug classes
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- HMG-CoA Reductase Inhibitor
- Anticholesteremic Agents
- Antimetabolites
- Enzyme Inhibitors
- Hypolipidemic Agents
- Lipid Regulating Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- AMLODIPINE BESYLATE AND ATORVASTATIN CALCIUM
- ATORVALIQ
- ATORVASTATIN CALCIUM
- Atorvaliq
- CADUET
- Caduet
- LIPITOR
- LIPTRUZET
- LYPQOZET
- Lipitor
- CI-981
- CI981
- atorvastatin calcium hydrate
- atorvastatin calcium anhydrous
- atorvastatin acid
- cardyl
- atorvastatin calcium
- atorvastatin calcium trihydrate
- ATORVASTATINE
- ATORVASTATINA
- Atorvastatin calcium
- Cardyl
- Prevencor
- Sortis
- Tahor
- Zarator
- Atogal
- Atorlip
- Atorpic
- Atorvastatina
- Atorvastatine
- Atorvastatinium
- Atrovastin
- Faboxim
- Lipotropic
- Lipovastatinklonal
- Liprimar
- Lowden
Reported adverse events
- Stevens-Johnson syndrome
- Rhabdomyolysis
- Arthralgia
- Insomnia
- Myalgia
- Myopathy
- Nasopharyngitis
- Nausea
- Dyspepsia
- Musculoskeletal pain
- Pain in extremity
- Urinary tract infection
Look up ATORVASTATIN in the interactive SynDRA portal →