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LASELIPAG
SynDRA canonical compound SYN0007732 — structure-anchored drug synonym record
| Primary target(s) | PTGIR |
|---|
| Mechanism of action | Platelet aggregation inhibitor |
|---|
All known targets
- PTGER2
- PTGIR
- PTGER1
- PTGER4
- PTGDR
- Ptgir
Mechanisms of action (all sources)
- Prostanoid receptor agonist
- Platelet aggregation inhibitor
- PTGER2 AGONIST
- PTGER4 AGONIST
- PTGIR FULL AGONIST
- PTGIR AGONIST
- Prostanoid IP receptor agonist
- IP1 prostacyclin receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- ADORA1
- HRH1
- HRH2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MAPK1
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGDR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- GSK3B
- GHSR
- FGFR3
- BRD4
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
Drug classes
- Prostacyclin Receptor Agonists
- Antihypertensive Agents
- Cardiovascular Agents
- Prostacyclin Receptor Agonist
ATC classes
- B01A · ANTITHROMBOTIC AGENTS
Cross-references
Synonyms
- ACT-333679
- ACT333679
- J2.120.976G
- MRE-269
- MRE269
- iloprost
- ACT 333679
- CHEBI:90848
- RefChem:552102
- DTXCID401584623
- MRE 269
- MFCD11976884
- E9PC7N0DID
- Selexipag active metabolite
- UNII-E9PC7N0DID
- laselipag [INN]
- OJQMKCBWYCWFPU-UHFFFAOYSA-N
- SCHEMBL676234
- GTPL5852
- orb1303362
- SCHEMBL29355314
- GLXC-04713
- HMS3748O13
- MRE-269?
- ARD193950
- BDBM50235387
- EBC-53056
- s5819
- AKOS027307832
- CS-6104
- SB19699
- T3S2007
- NCGC00476132-02
- AS-72199
- HY-79593
- MRE-269(ACT-333679)
- DB-119492
- MRE-269 (ACT-333679)
- EN300-384328
Reported adverse events
- Arthralgia
- Flushing
- Headache
- Myalgia
- Nausea
- Pain in extremity
- Rash
- Vomiting
- Decreased appetite
- Hyperthyroidism
- Injection
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