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QUINPIROLE
SynDRA canonical compound SYN0007720 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | DRD1 | DRD2 | DRD3 | DRD4 | HTR1A | HTR2A | HTR2B | HTR2C |
|---|
| Mechanism of action | dopamine receptor agonist |
|---|
All known targets
- DRD2
- DRD3
- DRD4
- DRD1
- HTR1A
- HTR2A
- HTR2B
- HTR2C
Mechanisms of action (all sources)
- Dopamine receptor agonist
- HTR1A FULL AGONIST
- HTR2A FULL AGONIST
- HTR2B FULL AGONIST
- HTR2C FULL AGONIST
- DRD2 FULL AGONIST
- DRD3 FULL AGONIST
- DRD4 FULL AGONIST
- DRD3 INHIBITOR
- DRD2 INHIBITOR
- DRD4 INHIBITOR
- DRD1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRB2
- ALOX15
- THRB
- TDP1
- RAPGEF4
- POLI
- OPRM1
- MPHOSPH8
- LMNA
- KCNH2
- HDAC6
- GMNN
- FEN1
- EHMT2
- DRD5
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CBX1
- BLM
- ARSA
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- 5HT2A
- 5HT2B
- 5HT2C
- ACES
- AHR
- CP2D6
- GPR151
- GRM5
- IFNG
Drug classes
Cross-references
Synonyms
- Quinpirol
- Quinpirolum
- Quinpirole [INN]
- Quinpirolum [Latin]
- Quinpirol [Spanish]
- UNII-20OP60125T
- CHEBI:75401
- LY 156258
- CHEMBL240773
- (4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo(3,4-g)quinoline
- 20OP60125T
- 1H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR-trans)-
- (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrido[2,3-f]indazole
- (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrazolo[3,4-g]quinoline
- BRD-K26548821
- quinpirol-(-)
- RefChem:930496
- DTXCID4028204
- NCGC00016954-05
- (4aR-trans)-; (-)-Quinpirole
- NSC_54562
- Quinpirole,(-)
- Tocris-1061
- A1JDS
- GTPL2
- Lopac-Q-102
- Lopac-Q-111
- Prestwick0_001093
- Prestwick1_001093
- Prestwick2_001093
- Prestwick3_001093
- Biomol-NT_000014
- QUINPIROLE [WHO-DD]
- Lopac0_000990
- Lopac0_001030
- SCHEMBL50905
- BSPBio_001166
- SPBio_003053
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