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GLIMEPIRIDE
SynDRA canonical compound SYN0007706 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ABCC8 |
|---|
| Mechanism of action | Insulin secretagogue |
|---|
| Indication | diabetes mellitus |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ABCC8
- KCNJ11
- ABCC9
- AKR1C3
- KCNJ1
Mechanisms of action (all sources)
- Insulin secretagogue
- KCNJ11 BLOCKER
- Sulfonylurea receptor 1, Kir6.2 blocker
- ABCC8 BLOCKER
- ABCC9 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- NR1I3
- NR1H4
- NR1H3
- NR1H2
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- NR1I2
- NR3C1
- GNAS
- OPRD1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
Drug classes
- Anti-Arrhythmia Agents
- Cardiovascular Agents
- Hypoglycemic Agents
- Immunologic Factors
- Immunosuppressive Agents
- Sulfonylurea
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- AMARYL
- AVANDARYL
- Amaryl
- DUETACT
- PIOGLITAZONE HYDROCHLORIDE AND GLIMEPIRIDE
- ROSIGLITAZONE MALEATE AND GLIMEPIRIDE
- diameprid
- glimax
- glimperide
- glirid
- Glimepirida
- HOE-490
- NSC-759809
- Glimepiride component of avandaryl
- Glimepiride component of duetact
- Niddaryl
- Amarel
- Endial
- Glimepirid
- Glimepiridum
- Glimepride
- Glimer
- Glymepirid
- Roname
- Solosa
- Glimepirida [Spanish]
- Glimepiridum [Latin]
- Sandoz glimepiride
- Hoe-490
- Amaryl (TN)
- Novo-glimepiride
- PMS-glimepiride
- Ratio-glimepiride
- Amaryl, Glista OD, Glimepiride
- Glimepiride [USAN:BAN:INN]
- Glimepiride (JAN/USP/INN)
- 64598P
Reported adverse events
- Headache
- Leukopenia
- Nausea
- Dizziness
- Thrombocytopenia
- Vomiting
- Porphyria
- Stevens-Johnson syndrome
- Dysgeusia
- Accident
- Injury
- Asthenia
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