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FLUTICASONE PROPIONATE
SynDRA canonical compound SYN0007661 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | Glucocorticoid receptor agonist |
|---|
| Indication | corticosteroid-responsive dermatoses |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- PGR
- NR3C2
- PLA2G4A
- CYP3A5
- CYP3A7
- Nr3c1
- Ar
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C2 AGONIST
- PGR AGONIST
- NR3C1 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- AR
- HTR3A
- MLNR
- MC4R
- MC3R
- MAOA
- KDR
- KCNH2
- HTR2C
- NPY2R
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HCAR2
- NPY1R
- ACHE
- GHSR
- PTGS2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SAMHD1
- PTGS1
- NTSR1
- PDE4D
- PDE4A
- PDE3A
- OPRM1
- OPRK1
- OPRD1
- GIPR
- GCGR
- ADORA1
- ADRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2C9
- CP3A4
- CP3A7
- ESRRA
- KSYK
- MCR
- MRGPRX1
- PRGR
- SYK
- T22D3
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Allergic Agents
- Anti-Asthmatic Agents
- Anti-Inflammatory Agents
- Bronchodilator Agents
- Dermatologic Agents
- Peripheral Nervous System Agents
- Respiratory System Agents
ATC classes
- D07A · CORTICOSTEROIDS, PLAIN
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- R03B · OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
- ADRENERGICS, INHALANTS
Cross-references
Synonyms
- ADVAIR DISKUS 100/50
- ADVAIR DISKUS 250/50
- ADVAIR DISKUS 500/50
- ADVAIR HFA
- AIRDUO DIGIHALER
- AIRDUO RESPICLICK
- ARMONAIR DIGIHALER
- ARMONAIR RESPICLICK
- AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE
- CUTIVATE
- Cutivate
- DYMISTA
- fluticasone proprionate
- flixotide
- fluticasone 17-propionate
- Fluticaps
- Fluticasone-17-propionate
- Opn-375
- Optinose
- CCI-18781
- CCI18781
- NSC-759889
- PF-00241939
- R01AD08
- Aerivio spiromax
- Airflusal forspiro
- Armonair digihaler
- Armonair respiclick
- Flixonase
- Flixotide
- Flonase allergy relief
- Flovent diskus 100
- Flovent diskus 250
- Flovent diskus 50
- Flovent hfa
- Fluticasone propionate component of advair
- Fluticasone propionate component of advair hfa
- Fluticasone propionate component of airduo respiclick
Reported adverse events
- Headache
- Hypersensitivity
- Epistaxis
- Cataract
- Glaucoma
- Cough
- Pharyngitis
- Nausea
- Immunosuppression
- Rhinitis
- Infection
- Urticaria
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