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RIFAMYCIN
SynDRA canonical compound SYN0007607 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | SLCO1A2 | SLCO1B1 | SLCO1B3 | SLCO2B1 |
|---|
| Mechanism of action | DNA directed RNA polymerase inhibitor |
|---|
| Indication | leprosy | tuberculosis |
|---|
| Disease area | infectious disease |
|---|
All known targets
- SLCO1A2
- SLCO1B1
- SLCO1B3
- SLCO2B1
- ABCB11
- Abcb11
- Bact sigA
- MycB rpoA
- MycB rpoB
- MycB rpoC
- MycB rpoZ
- Stap-coc rpoB
Mechanisms of action (all sources)
- SLCO1A2 INHIBITOR
- SLCO1B1 INHIBITOR
- SLCO1B3 INHIBITOR
- SLCO2B1 INHIBITOR
- DNA directed RNA polymerase inhibitor
- RNA synthesis inhibitor
- Bact sigA MODULATOR
- Stap-coc rpoB MODULATOR
- MycB rpoA; MycB rpoB; MycB rpoC; MycB rpoZ INHIBITOR
- rpoB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TBXA2R
- ADRA1A
- HTR2B
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- KCNH2
- ABCC1
- ACHE
- HRH3
- F2
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2A
- ADORA3
- HTR1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Rifamycin Antibacterial
- Antirheumatic Agents
- Anti-Bacterial Agents
ATC classes
- S02A · ANTIINFECTIVES
- A07A · INTESTINAL ANTIINFECTIVES
- J04A · DRUGS FOR TREATMENT OF TUBERCULOSIS
- D06A · ANTIBIOTICS FOR TOPICAL USE
Cross-references
Synonyms
- AEMCOLO
- Aemcolo
- aemcolo
- rifacin
- rifamycin sodium
- CB-01-11
- Rifamycin SV
- Rifamycine
- Rifamicina
- Rifamicine sv
- Rifomycin
- Rifomycin sv
- M-14
- Rifamycin SV MMX
- Rifamycin sodium
- Rifamycin (oral controlled-release, gastrointestinal-specific)
- Rifamycin (oral controlled-release, gastrointestinal-specific), Cosmo/Dr Falk/Santarus
- Rifomycin SV
- rifamycin-sv
- rifamycin sv (ep impurity)
- rifaximin impurity c (ep impurity)
- Rifamicine SV
- DU69T8ZZPA
- Rifamycinum
- Rifocyn
- RIFOMYCIN
- CHEBI:29673
- Rifamycine Chibret
- RefChem:57064
- DTXCID9012014
- CHEBI:26580
- A07AA13
- D06AX15
- J04AB03
- S02AA12
- Rifamycins
- Rifomycins
- Rifocin
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