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ALLOPURINOL
SynDRA canonical compound SYN0007579 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | XDH |
|---|
| Mechanism of action | Xanthine oxidase inhibitor |
|---|
| Indication | gout | kidney stones |
|---|
| Disease area | rheumatology | urology |
|---|
All known targets
- XDH
- ADORA2A
- HPRT1
- Xdh
- stxA
Mechanisms of action (all sources)
- Xanthine oxidase inhibitor
- XDH INHIBITOR
- Xanthine dehydrogenase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR2
- ADRA1A
- SLC6A4
- MMP1
- MAPK14
- MAPK3
- MC3R
- MC4R
- MC5R
- MLNR
- ABCB11
- MAOA
- MMP9
- NFE2L2
- NPY1R
- NPY2R
- NR3C1
- NTSR1
- MAPK1
- LCK
- LMNA
- OPRK1
- KDR
- KCNH2
- IDH1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- OPRD1
- OPRM1
- HCAR2
- SLC29A1
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Xanthine Oxidase Inhibitors
- Antimetabolites
- Antioxidants
- Antirheumatic Agents
- Enzyme Inhibitors
- Free Radical Scavengers
- Gout Suppressants
- Noxae
- Xanthine Oxidase Inhibitor
ATC classes
- M04A · ANTIGOUT PREPARATIONS
Cross-references
Synonyms
- ALLOPURINOL SODIUM
- ALOPRIM
- Aloprim
- DUZALLO
- LOPURIN
- ZYLOPRIM
- Zyloprim
- zyloprim
- allopurinol sodium
- Alopurinol
- Allopurinolum
- Suspendol
- Takanarumin
- BW-56-158
- NSC-101655
- NSC-1390
- Allopurinol component of duzallo
- Aloral
- Aluline 100
- Aluline 300
- Caplenal
- Cosuric
- Hamarin 100
- Hamarin 300
- Ledopur
- Lopurin
- Uricto
- Xanthomax-100
- Xanthomax-300
- Zyloric
- Zyloric-300
- Adenock
- Ailural
- Ailurial
- Allohexal
- Allohexan
- Alloprin
Reported adverse events
- Rash
- Stevens-Johnson syndrome
- Renal failure
- Thrombocytopenia
- Infertility
- Ecchymosis
- Epistaxis
- Erythema
- Erythema multiforme
- Hepatic necrosis
- Myopathy
- Hypersensitivity
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