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DICUMAROL
SynDRA canonical compound SYN0007555 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | VKORC1 |
|---|
| Mechanism of action | NADPH inhibitor |
|---|
| Indication | deep vein thrombosis (DVT) |
|---|
| Disease area | hematology |
|---|
All known targets
- VKORC1
- NQO1
- Akr1b1
- CRYZ
- CYP2C9
- GPR35
- MAPK1
- Nqo1
- PCSK7
- fabI
- hisG
Mechanisms of action (all sources)
- NADPH inhibitor
- VKORC1 INHIBITOR
- Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PDE4D
- ESR1
- ABCB11
- MAOA
- NR1I2
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- LMNA
- OPRD1
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- NR3C1
- OPRK1
- GMNN
- SLC6A2
- USP1
- TSHR
- TP53
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2C9
- CP3A7
- ESRRA
- IP6K1
- NF2L2
- NSD2
- PPARG
Drug classes
- Anticoagulants
- Enzyme Inhibitors
- Hematologic Agents
- Uncoupling Agents
ATC classes
- B01A · ANTITHROMBOTIC AGENTS
Cross-references
Synonyms
- dicoumarol
- dicoumal
- dicoumarin
- dicuman
- dicumarine
- Dicoumarol
- Bishydroxycoumarin
- Dicoumarolum
- NSC-17860
- NSC-221570
- NSC-41834
- Acadyl
- Acavyl
- Anathrombase
- Antitrombosin
- Apekumarol
- Baracoumin
- Cuma
- Cumid
- Dicoumal
- Dicoumarin
- Dicoumerol
- Dicuman
- Dicumarine
- Dicumarinum
- Dicumarolo
- Dicumarolum
- Dicumol
- Dikumarol
- Dufalone
- Dwukumarol
- Kumoran
- Melitoxin
- Temparin
- Trombosan
- Dicumaol R
- Dicumarol [USAN]
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