← SynDRA

FLUCYTOSINE

SynDRA canonical compound SYN0007546 — structure-anchored drug synonym record

All known targets

• Candi TMP1
• DNMT1
• HSP82
• HTR2A
• TMP1

Mechanisms of action (all sources)

• Candi TMP1 INHIBITOR
• TMP1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• CASP1
• ACHE
• OPRD1
• NR1I2
• NPY2R
• NPY1R
• MMP9
• MMP1
• MLNR
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• MAOA
• LCK
• KCNH2
• HTR6
• HTR3A
• HTR2C
• HTR2B
• HTR1A
• HRH2
• HRH1
• HMGCR
• HDAC6
• NR3C1
• OPRK1
• GHSR
• OPRM1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC6A2
• SLC29A1
• SIGMAR1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ANDR
• IFNG
• MCL1

Drug classes

• Nucleoside Analog Antifungal
• Anti-Infective Agents
• Antifungal Agents
• Antimetabolites
• Noxae
• other antifungal

ATC classes

• J02A · ANTIMYCOTICS FOR SYSTEMIC USE
• D01A · ANTIFUNGALS FOR TOPICAL USE

Cross-references

• PubChem CID: 3366
• ChEMBL: CHEMBL1463
• DrugBank: DB01099
• ChEBI: CHEBI:5100
• KEGG: D00323
• RxNorm: 4451
• PDB: 1LD
• Wikipedia: Flucytosine
• TTD: D0S5WG
• LINCS BRD: BRD-K82143716

Synonyms

• ANCOBON
• Ancobon
• Ro 2-9915
• ancotil
• ancobon
• 5-fluorocytosine
• Flucitosina
• Flucytosinum
• NSC-103805
• RO-2-9915
• RO-29915
• Alcobon
• Ancoban
• Ancotil
• Flourocytosine
• Fluorocytosine
• Ancotyl
• Flucystine
• Flucytosin
• Flucytosone
• Fluocytosine
• Fluorcytosine
• Flucitosina [DCIT]
• F0321
• LT00771985
• Ancobon (TN)
• Flucytosinum [INN-Latin]
• GL663142 & 5FC
• Ro-2-9915
• Ro 29915 E/265601
• Flucytosine (JP15/USP/INN)
• Flucytosine [USAN:INN:BAN:JAN]
• Cytosine, 5-fluoro-(6CI,7CI,8CI)
• GL663142 & 4-Amino-5-fluoropyrimidin-2(1H)-one
• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-)
• 4-Amino-5-fluoro-2(1H)-pyrimidinone
• 4-Amino-5-fluoropyrimidin-2(1H)-one

Reported adverse events

• Ataxia
• Cardiac arrest
• Fatigue
• Nausea
• Rash
• Respiratory arrest