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AMISULPRIDE
SynDRA canonical compound SYN0007448 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | DRD3 |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | bipolar disorder | psychosis | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- DRD3
- HTR2A
- HTR1B
- HTR6
- HTR2B
- HTR1D
- HTR7
- HTR1A
- HTR1E
- HTR1F
- HTR2C
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- HTR1F ANTAGONIST
- Serotonin (5-HT) receptor antagonist
- HTR2B ANTAGONIST
- HTR4 ANTAGONIST
- HTR1B ANTAGONIST
- HTR3A ANTAGONIST
- HTR1A ANTAGONIST
- HTR1D ANTAGONIST
- HTR2A ANTAGONIST
- HTR2C ANTAGONIST
- HTR1E ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2B
- ADORA1
- PDE3A
- LMNA
- MAOA
- MAPK1
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE4D
- HRH3
- PGR
- PPARG
- PTGS2
- SAMHD1
- SETD7
- SLC29A1
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- KCNH2
- HRH2
- ADORA2A
- CHRM1
- ADORA3
- ADRA1A
- ADRB1
- ADRB2
- AGTR1
- ALOX15
- AVPR1A
- AVPR2
- BDKRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antidepressive Agents
- Antidepressive Agents, Second-Generation
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
- Dopamine D2 Antagonists
- Dopamine-2 Receptor Antagonist
ATC classes
Cross-references
Synonyms
- BARHEMSYS
- Barhemsys
- barhemsys
- aminosultopride
- deniban
- solian
- Amisulprida
- Aminosultopride
- Deniban
- Socian
- Sulamid
- APD-421
- APD421
- DAN-2163
- NSC-760085
- Solian
- Solian 100
- Solian 200
- Solian 400
- Solian 50
- Amisulpiride
- Amisulpridum
- Amisulpride [INN]
- Amisulprida [INN-Spanish]
- Amisulpride (INN)
- Amisulpridum [INN-Latin]
- Deniban (TN)
- Solian (TN)
- Solian, Amisulpride
- SL-91.1077
- C17H27N3O4S
- Amisulpride free base
- NSC 760085
- CHEBI:64045
- 71675-85-9 (free base)
- 8110R61I4U
- NCGC00092310-03
- Sulpitac
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