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MYCOPHENOLATE MOFETIL
SynDRA canonical compound SYN0007406 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HCAR2 | IMPDH1 | IMPDH2 |
|---|
| Mechanism of action | dehydrogenase inhibitor | inositol monophosphatase inhibitor |
|---|
| Indication | organ rejection |
|---|
| Disease area | transplant |
|---|
All known targets
- IMPDH2
- IMPDH1
- HCAR2
- PTGER2
Mechanisms of action (all sources)
- IMPDH1 INHIBITOR
- Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
- IMPDH2 INHIBITOR
- dehydrogenase inhibitor
- inositol monophosphatase inhibitor
- PTGER2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- NR1I2
- MMP9
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- GHSR
- FYN
- MMP1
- ABCB11
- FLT1
- PTGS2
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- ANDR
- CP2C9
- CP2D6
- CP3A4
- CP3A7
- ESRRA
- IFNG
- KSYK
- NF2L2
- NR1H4
- NSD2
- PPARG
- SYK
- TP53
- YAP1
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibiotics, Antineoplastic
- Antibiotics, Antitubercular
- Antineoplastic Agents
- Antitubercular Agents
- Enzyme Inhibitors
- Antimetabolite Immunosuppressant
ATC classes
- L04A · IMMUNOSUPPRESSANTS
Cross-references
Synonyms
- CELLCEPT
- MYCOPHENOLATE MOFETIL HYDROCHLORIDE
- MYHIBBIN
- Myhibbin
- linfonex
- RS-61443
- myclausen
- mycophenolate mofetil hydrochloride
- myfenax
- mycophenolate mofetil HCl
- Mycophenolic acid 2-(4-morpholinyl)ethyl ester
- Myclausen
- Mycophenylate mofetil
- NSC-724229
- NSC-758905
- Arzip
- Cellcept
- Mycophenolate mofetil teva
- Myfenax
- CellCept
- Munoloc
- Mycophenolic acid morpholinoethyl ester
- TM-MMF
- Mycophenolatemofetil
- UNII-9242ECW6R0
- HSDB 7436
- Cellcept (TN)
- CHEBI:8764
- C23H31NO7
- Mycophenolate mofetil (CellCept)
- 9242ECW6R0
- RS-61443-190
- MMF
- ME-MPA
- MMF CellCept(TM)
- R-99
- Mycophenolate mofetil (JAN/USAN)
Reported adverse events
- Infection
- ECT
- Se
- Asthenia
- Constipation
- Headache
- Hypertension
- Hypotension
- Rash
- Tremor
- Vomiting
- Abdominal pain
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