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ALTRETAMINE
SynDRA canonical compound SYN0007405 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Mechanism of action | DNA synthesis inhibitor |
|---|
| Indication | ovarian cancer |
|---|
| Disease area | oncology |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- KAT2A
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH3
- HRH2
- HRH1
- HMGCR
- NR1I2
- NR3C1
- OPRD1
- SIGMAR1
- THRB
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- NF2L2
- PLCG1
- PRGR
Drug classes
- Alkylating Activity
- Alkylating Drug
- Alkylating Agents
- Antineoplastic Agents
- Antineoplastic Agents, Alkylating
- Noxae
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- HEXALEN
- hexalen
- hexamethylmelamine
- hexylen
- Altretamina
- Hexamethylmelamine
- NSC-13875
- Hexalen
- Hexastat
- Altretaminum
- HEXAMETHYLMELAMINE
- HMM
- HTM
- HXM
- Hemel
- Hexinawas
- Altretamine Bellon Brand
- Altretamine Chiesi Brand
- Altretamine Wassermann Brand
- Bellon Brand of Altretamine
- Chiesi Brand of Altretamine
- MGI Pharma Brand of Altretamine
- Rhone-Poulenc Rorer Brand of Altretamine
- Wassermann Brand of Altretamine
- A 8723
- ENT 50852
- NC 195
- Altretamina [INN-Spanish]
- Altretaminum [INN-Latin]
- Hexalen (TN)
- Hexalen, Altretamine
- KB-913
- Altretamine (USP/INN)
- Altretamine [USAN:INN:BAN]
- No-s-triazine
- N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
- 2,4, 6-Tris(dimethylamino)-1,3,5-triazine
- 2,4,6-Tris(dimethylami
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