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SULPHADOXINE
SynDRA canonical compound SYN0007403 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Mechanism of action | dihydropteroate synthase inhibitor |
|---|
| Indication | malaria |
|---|
| Disease area | infectious disease |
|---|
All known targets
- Bact folP
- MAOB
- PF3D7_0810800
- PPPK-DHPS
Mechanisms of action (all sources)
- dihydropteroate synthase inhibitor
- Bact folP BINDER
- MAOB INHIBITOR
- PPPK-DHPS INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- KCNH2
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- HTR6
- FLT1
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- MMP9
- NPY1R
- NPY2R
- NR3C1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- PTPRC
- PTGS2
- PTGS1
- PTAFR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Infective Agents
- Anti-Infective Agents, Urinary
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- Sulfonamide
ATC classes
Cross-references
Synonyms
- FANSIDAR
- Sulforthomidine
- Fanasil
- Sulphormethoxine
- Sulfadoxinum
- Sulfadoxina
- Sulfadoxin
- Fanzil
- Solfadossina
- Ro-4-4393
- Solfadossina [DCIT]
- Sulfadoxinum [INN-Latin]
- Sulfadoxina [INN-Spanish]
- 4-Sulfanilamido-5,6-dimethoxypyrimidine
- WR 4873
- UNII-88463U4SM5
- Orthosulfin
- Sulformethoxine
- Sulformetoxine
- Sulphormetoxin
- Sulphorthodimethoxine
- WR 4073
- Sanasil: Sulfadoxine: Sulformetoxin
- Sulfadoxine (JAN/USP/INN)
- Sulfadoxine [USAN:INN:BAN:JAN]
- 6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
- RS-1653
- Dimethoxy-sulfanilamido-diazine
- fanasil
- HMS1571K10
- CAS-2447-57-6
- BPBio1_001286
- Fanasulf
- Sulphadoxine / pyrimethamine
- Fansidar (TN)
- Sulfadoxine component of fansidar
- Sulfadoxine and pyrimethamine
- sulformetoxin
- SULFADOXINE [ORANGE BOOK]
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