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TRIAMCINOLONE
SynDRA canonical compound SYN0007263 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | Glucocorticoid receptor agonist |
|---|
| Indication | corticosteroid-responsive dermatoses |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- ANXA1
- PGR
- SERPINA6
- CYP3A5
- CYP3A7
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 MODULATOR
- glucocorticoid receptor agonist, immunosuppressant
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- CYP2J2
- ACHE
- KDR
- MMP1
- MC5R
- MC4R
- MC3R
- MBNL1
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- NFE2L2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH3
- HRH2
- HRH1
- HMGCR
- HIF1A
- MMP9
- NFKB1
- GMNN
- PTPRC
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SMAD3
- SLCO1B3
- SLCO1B1
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ACM5
- ANDR
- CFTR
- CP2C9
- CPT1C
- MRP1
- NF2L2
- NSD2
- PRGR
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Glucocorticoids
- Hormones
- Enzyme Inhibitors
- Immunologic Factors
- Immunosuppressive Agents
- immunosuppressant
- anti-inflammatory agent
ATC classes
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- R03B · OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- S01B · ANTIINFLAMMATORY AGENTS
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- D07A · CORTICOSTEROIDS, PLAIN
- A01A · STOMATOLOGICAL PREPARATIONS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
- CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Cross-references
Synonyms
- ARISTOCORT
- KENACORT
- Nasacort
- triamcinlon
- triamcinolon
- rodinolone
- Triamcinolona
- NSC-13397
- Aristocort
- Delphicort
- Kenacort
- Volon
- Adcortyl
- Celeste
- Cinolone
- Fluoxiprednisolone
- Fluoxyprednisolone
- Fougera
- Ione
- Ledercort
- Mycolog
- Omcilon
- Omicilon
- Orion
- Rodinolone
- Tiamcinolonum
- Triamcet
- Triamcinalone
- Triamcinlon
- Triamcinolon
- Triamcinolonum
- Tricortale
- Trilone
- Tristoject
- Aristocort Tablets
- Triamcinolonum [INN]
- CL 19823
Reported adverse events
- Perioral dermatitis
- Acne
- Arachnoiditis
- Bradycardia
- Exophthalmos
- Spinal cord infarction
- Hypertrichosis
- Folliculitis
- Skin atrophy
- Cough
- Anaphylactoid reaction
- Dyspepsia
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