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MILRINONE
SynDRA canonical compound SYN0007185 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PDE3A |
|---|
| Mechanism of action | Phosphodiesterase inhibitor |
|---|
| Indication | congestive heart failure |
|---|
| Disease area | cardiology |
|---|
All known targets
- PDE3A
- PDE3B
- PDE5A
- PDE2A
- PDE4A
- PDE4B
- PDE4C
- PDE4D
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- PDE3A INHIBITOR
- Phosphodiesterase 3A inhibitor
- PDE2A INHIBITOR
- PDE3B INHIBITOR
- PDE5A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- PTGS1
- ACHE
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDR
- KDM4E
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- HDAC6
- NPY2R
- NR3C1
- ADORA1
- OPRD1
- TTK
- TSHR
- TDP1
- TBXAS1
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Phosphodiesterase 3 Inhibitors
- Phosphodiesterase 3 Inhibitor
- Cardiotonic Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Hematologic Agents
- Phosphodiesterase Inhibitors
- Platelet Aggregation Inhibitors
- Protective Agents
- Vasodilator Agents
ATC classes
- C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
Cross-references
Synonyms
- MILRINONE LACTATE
- MILRINONE LACTATE IN DEXTROSE 5%
- MILRINONE LACTATE IN DEXTROSE 5% IN PLASTIC CONTAINER
- MILRINONE LACTATE IN PLASTIC CONTAINER
- PRIMACOR
- PRIMACOR IN DEXTROSE 5% IN PLASTIC CONTAINER
- primacor
- corotrop
- corotrope
- milrinone lactate
- Milrinona
- Milrila
- NSC-760072
- WIN 47,203-2
- WIN-47203-2
- Corotrop
- Corotrope
- Milrinonum
- Primacor
- Milrinona [Spanish]
- Milrinonum [Latin]
- M 4659
- M1663
- YM 018
- Milrila (TN)
- Primacor (TN)
- Win-47203-2
- Win-47203
- Milrinone [USAN:BAN:INN]
- Milrinone (JAN/USAN/INN)
- 111GE027
- JU9YAX04C7
- milrinone (usp monograph)
- NSC 760072
- WIN 47203-2
- milrinone (usp-rs)
- WIN 47203
- DTXCID103324
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