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ATOVAQUONE
SynDRA canonical compound SYN0007078 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | mitochondrial electron transport inhibitor |
|---|
| Indication | pneumonia |
|---|
| Disease area | infectious disease |
|---|
All known targets
- ABCG2
- DHODH
- Dhodh
- MT-CYB
- Malaria DHOdehase
- dhod
Mechanisms of action (all sources)
- mitochondrial electron transport inhibitor
- Malaria DHOdehase INHIBITOR
- MT-CYB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- OPRD1
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRK1
- ADORA2A
- OPRM1
- PDE3A
- PDE4D
- PGR
- PSAP
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- HRH3
- HRH2
- HRH1
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Drug classes
- Antimalarial
- Antiprotozoal
- Anti-Infective Agents
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- Enzyme Inhibitors
ATC classes
- P01A · AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
- ANTIMALARIALS
Cross-references
Synonyms
- ATOVAQUONE AND PROGUANIL HYDROCHLORIDE
- MALARONE
- MALARONE PEDIATRIC
- MEPRON
- Mepron
- 566C80
- mepron
- Atovacuona
- 566C
- NSC-759582
- Atovaquone component of malarone
- Atovaquone component of malarone pediatric
- Wellvone
- Acuvel
- Atavaquone
- Pron
- Atovaquone GlaxoSmithKline brand
- Glaxo Wellcome brand of atovaquone
- GlaxoSmithKline brand of atovaquone
- Malarone Pediatric
- BW 566C
- BW 566C80
- Hydroxynaphthoquinone 566C80
- Atovaquone & Interleukin 12
- BW 556C-80
- BW 566C-80
- BW-A 566C
- DRG-0084
- Hydroxynaphthoquinone, 566C80
- Mepron (TN)
- Mepron (antipneumocystic)
- ATO & IL-12
- Atovaquone (USP/INN)
- Atovaquone [USAN:BAN:INN]
- CRL-8131 & Atovaquone
- 566C80 hydroxynaphthoquinone
- 566C80, hydroxynaphthoquinone
Reported adverse events
- Insomnia
- Nausea
- Vomiting
- Stevens-Johnson syndrome
- Headache
- Hepatotoxicity
- Cough
- Erythema
- Erythema multiforme
- Hepatitis
- Hypersensitivity
- Pancreatitis
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