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STRYCHNINE
SynDRA canonical compound SYN0006963 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | GLRA1 |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
All known targets
- GLRA1
- CHRM1
- CHRM2
- GLRA2
- GLRA3
- CHRM4
- CHRM3
- CHRNA10
- CHRNA9
- CHRM5
- GLRB
- TAS2R10
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- GLRA1 ANTAGONIST
- GLRA2 ANTAGONIST
- GLRA3 ANTAGONIST
- TAS2R10 AGONIST
- TAS2R46 AGONIST
- CHRM1 NEGATIVE ALLOSTERIC MODULATOR
- CHRM1 NEUTRAL
- CHRM2 POSITIVE ALLOSTERIC MODULATOR
- CHRM3 NEGATIVE ALLOSTERIC MODULATOR
- CHRM4 POSITIVE ALLOSTERIC MODULATOR
- CHRM5 NEGATIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ACHE
- MC5R
- NR3C1
- NPY2R
- NPY1R
- NEIL2
- NEIL1
- MUTYH
- MPG
- MMP9
- MMP1
- MC4R
- OGG1
- MC3R
- MBD4
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KAT2A
- HTR6
- NTHL1
- OPRD1
- HTR2B
- OPRK1
- UNG
- TDP1
- TDG
- TBXAS1
- TACR2
- TACR1
- SMUG1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- ACH10
- ACHA9
- ACM1
- ACM2
- ACM3
- ACM4
- ACM5
- CP2D6
- CP3A4
- PE2R2
Drug classes
- Central Nervous System Agents
- Central Nervous System Stimulants
- Convulsants
- Glycine Agents
- Neurotransmitter Agents
- Noxae
- Poisons
Cross-references
Synonyms
- Strychnidin-10-one
- (-)-Strychnine
- strychnin
- strychnine hydrochloride
- strychnine sulfate
- strychnine HCl
- Strychninum
- NSC-5365
- [3H]strychnine
- Strychnin
- UNII-H9Y79VD43J
- Sanaseed
- CHEBI:28973
- Estricnina
- Strychinos
- Strychnos
- Gopher-gitter
- Gopher bait
- Mouse-nots
- Mole death
- Boomer-rid
- Mouse-rid
- H9Y79VD43J
- Mouse-tox
- Kwik-kil
- Hare-Rid
- Dolco mouse cereal
- Strychnin [German]
- Stricnina [Italian]
- Pied piper mouse seed
- Caswell No 805
- Strychnine [BSI:ISO]
- RCRA waste number P108
- (-)-Strychnine, 98%
- HSDB 2001
- NSC 5365
- EINECS 200-319-7
- UN1692
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