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BENZBROMARONE
SynDRA canonical compound SYN0006814 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ABCC1 | SLC22A12 |
|---|
| Mechanism of action | chloride channel blocker |
|---|
| Indication | gout |
|---|
| Disease area | rheumatology |
|---|
All known targets
- SLC22A12
- ABCC1
- ABCG2
- env
- PTPN1
- PIEZO1
- PDE4A
- PA
- NR1H4
- MAPK14
- MAPK1
- HTR2B
Mechanisms of action (all sources)
- SLC22A12 INHIBITOR
- Solute carrier family 22 member 12 inhibitor
- PIEZO1 INHIBITOR
- chloride channel blocker
- ABCC1 STIMULATOR
- ANO1 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- ALB
- KCNH2
- ESR1
- CYP2J2
- NR1I2
- CYP2C19
- PDE3A
- PDE4D
- PGR
- PPARG
- CHRM2
- SLC22A6
- HRH1
- ADRA2A
- TTR
- ADRA1A
- THRB
- TBXAS1
- MC5R
- MLNR
- MMP1
- MMP9
- NPY1R
- NPY2R
- MC3R
- USP2
- USP1
- NR2E3
- NR3C1
- OPRD1
- MC4R
- MAPT
- OPRM1
- MAPK3
- MAOA
- VDR
- LMNA
- LCK
- VIPR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALOX12
- PLIN5
- MDR1
- NCOR2
- NOD1
- NOD2
- NTM1A
- NTMT1
- PA21B
- PE2R2
- PHGDH
- PLIN1
- PPM1D
- ALR
- PRGR
- RPGF3
- RPGF4
- S12A5
- S1PR1
- TNF
- TNNC1
- TNNI3
- TNNT2
- TP53
- MCL1
- LRC26
- LOX12
- KCNQ1
- ANDR
- ATG4B
- CP1A2
- CP2C9
- CP3A7
- CRHBP
- CRHR2
- DPOLB
- GCR
- GEMI
- HCRTR1
- HSPB1
Drug classes
- Antirheumatic Agents
- Gout Suppressants
- Uricosuric Agents
ATC classes
- M04A · ANTIGOUT PREPARATIONS
Cross-references
Synonyms
- benzbromaron
- azubromaron
- Benzbromarona
- Benzbromaron
- Benzpromarone
- Uroleap
- L-2214
- MJ-10061
- NSC-85433
- Desuric
- Narcaricin mite
- Acifugan
- Azubromaron
- Benzbromaronratiopharm
- Benzbromaronum
- Benzobromarona
- Besuric
- Exurate
- Harolan
- Hipurik
- Minuric
- Narcaricin
- Normurat
- Uricovac
- Urinorm
- Aliud Brand of Benzbromarone
- Benzbromaron AL
- Benzbromaron-ratiopharm
- Benzbromarone Aliud Brand
- Benzbromarone Heumann Brand
- Benzbromarone Sanfer Brand
- Benzbromarone ratiopharm Brand
- Heumann Brand of Benzbromarone
- Ratiopharm Brand of Benzbromarone
- Sanfer Brand of Benzbromarone
- Sanofi Winthrop Brand of Benzbromarone
- L2214
- MJ 10061
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