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STAUROSPORINE
SynDRA canonical compound SYN0006770 — structure-anchored drug synonym record
| Primary target(s) | GSK3B |
|---|
| Mechanism of action | PKC inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PKC inhibitor
- IKBKB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PAK4
- PHKG1
- PEAK1
- PDPK1
- PDK1
- PDGFRB
- PDGFRA
- PBK
- PASK
- PAK6
- PAK5
- PAK3
- PI4KB
- PAK2
- PAK1
- OXSR1
- OSR1
- NUAK2
- NUAK1
- NTRK3
- NTRK2
- NTRK1
- NOX4
- PHKG2
- PIK3C2G
- NIM1K
- PLK1
- PRKCA
- PRKACG
- PRKACB
- PRKACA
- PRKAA2
- PRKAA1
- PNCK
- PLK4
- PLK3
- PLK2
- PKN3
- PIK3CA
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AAKB1
- M3K8
- MK10
- MK09
- MK08
- MK03
- MK01
- MAPK5
- M4K5
- M4K4
- M4K2
- M3K9
- M3K5
- MK13
- KSYK
- KS6B1
- KS6A6
- KS6A5
- KS6A4
- KS6A3
- KS6A2
- KS6A1
- KPCZ
- KPCT
- MK12
- MK14
- AAPK1
- PRKAG1
- VGFR3
- VGFR2
- VGFR1
- TSSK1
- TP53
- TELO2
- SLTM
- SLC12A7
- RNASE3
- RASH
- PRKAB1
- MNAT1
Drug classes
Cross-references
Synonyms
- Staurosporin
- (+)-Staurosporine
- Antibiotic 230
- Antibiotic AM 2282
- CCRIS 3272
- AM-2282
- UNII-H88EPA0A3N
- Alkaloid AM-2282 from Streptomyces
- H88EPA0A3N
- CHEMBL388978
- CHEBI:15738
- CGP 39360
- 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
- Antibiotic AM-2282
- AM 2282
- NSC618487
- RefChem:889116
- DTXCID201340061
- C28H26N4O3
- methoxy-methyl-(methylamino)[?]one
- SR-00000001485
- Staurosporin, 4
- 1nvr
- 1stc
- 1xbc
- 1xjd
- 1yhs
- 2gcd
- Staurosporine, 8
- Staurosporine & TNF
- Staurosporine (GMP)
- 1q3d
- 1sm2
- 2dq7
- STAUROSPORINE [MI]
- MolMap_000047
- SCHEMBL8157
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