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TIPRANAVIR
SynDRA canonical compound SYN0006748 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- ABCB1
- CTSD
- CTSE
- HIV PR
- PGA5
- Zmpste24
- pol
Mechanisms of action (all sources)
- protease inhibitor
- HIV PR MODULATOR
- pol INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- CHRM2
- NR1I2
- HTR2B
- ADORA3
- ADRA1A
- ADRA2A
- PPARG
- PTGS2
- MC3R
- MLNR
- HTR3A
- MAOA
- KDR
- OPRD1
- HTR2C
- HTR2A
- HTR1A
- NR3C1
- PDE4D
- OPRM1
- PDE3A
- HRH1
- PGR
- SCN5A
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- SLCO2B1
- HRH3
- GHSR
- HDAC6
- ABCC2
- ACE
- ACHE
- ADORA1
- ADORA2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2D6
- CP3A7
- GCR
- GPX4
- KSYK
- SYK
Drug classes
- HIV Protease Inhibitors
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Protease Inhibitor
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- APTIVUS
- Aptivus
- aptivus
- PNU 140690
- U-140690
- TPV
- PNU-140690
- Aptivus (Boehringer Ingelheim)
- Aptivus (TN)
- Aptivus(TM)
- PNU-140690E
- Tipranavir (INN)
- U 140690
- CHEBI:63628
- ZZT404XD09
- TIPRANAVIR [INN]
- Tipranavir [INN:BAN]
- UNII-ZZT404XD09
- HSDB 8083
- NCGC00182028-01
- 1d4y
- 2o4l
- 2o4n
- 2o4p
- TIPRANAVIR [MI]
- TIPRANAVIR [VANDF]
- TIPRANAVIR [MART.]
- TIPRANAVIR [WHO-DD]
- SCHEMBL40629
- SCHEMBL40630
- TIPRANAVIR [EMA EPAR]
- CHEMBL183041
- CHEMBL222559
- DTXSID6048622
- TIPRANAVIR [ORANGE BOOK]
- EX-A4113
- Tox21_112962
- BDBM50479982
Reported adverse events
- Hepatotoxicity
- Abdominal pain
- Abdominal pain upper
- Dehydration
- Fatigue
- Headache
- Insomnia
- Myalgia
- Nausea
- Neutropenia
- Pyrexia
- Rash
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