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CEFUROXIME
SynDRA canonical compound SYN0006716 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | bacterial cell wall synthesis inhibitor |
|---|
| Indication | gram-negative bacterial infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CA2
- MMP2
- MMP9
- dacA
- dacB
- dacC
- ftsI
- mrcA
- mrcB
- mrdA
- pbpA
Mechanisms of action (all sources)
- bacterial cell wall synthesis inhibitor
- mrcA INHIBITOR
- mrcB INHIBITOR
- dacC INHIBITOR
- mrdA INHIBITOR
- ftsI INHIBITOR
- dacA INHIBITOR
- dacB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PGR
- NR1I2
- ABCC2
- MAPT
- OPRD1
- NR3C1
- NPY1R
- MLNR
- MC3R
- MAOA
- OPRM1
- KDM4A
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- OPRK1
- PDE3A
- ABCC3
- SLC22A8
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- PTGS2
- PDE4D
- PPARG
- POLK
- POLI
- POLH
- POLB
- PKM
- HSD17B10
- HRH3
- HRH2
- HRH1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CTDS1
- IF4H
- PABP1
- PSIP1
- UHRF1
Drug classes
- Cephalosporin Antibacterial
- Anti-Bacterial Agents
- Anti-Infective Agents
ATC classes
- J01D · OTHER BETA-LACTAM ANTIBACTERIALS
- S01A · ANTIINFECTIVES
- COMBINATIONS OF ANTIBACTERIALS
Cross-references
Synonyms
- CEFUROXIME AND DEXTROSE IN DUPLEX CONTAINER
- CEFUROXIME SODIUM
- CEFUROXIME SODIUM IN PLASTIC CONTAINER
- KEFUROX
- KEFUROX IN PLASTIC CONTAINER
- ZINACEF
- ZINACEF IN PLASTIC CONTAINER
- biofuroxim
- cefaloxime
- cefasyn
- cefuroxim
- cefuroxime acid
- cephuroxime
- cefuroxime sodium
- cefuroxime sodium salt
- Cefuroxima
- Cefuroxime acid
- Cefuroximine
- 640/359
- Anaptivan
- Biociclin
- Biofuroksym
- Bioxima
- CXM
- Cefofix
- Cefumax
- Cefurex
- Cefuril
- Cefuroxim
- Cefuroximesodium
- Cefuroximo
- Cefuroximum
- Cephuroxime
- Cetroxil
- Colifossim
- Curocef
- Curoxim
- Curoxima
Reported adverse events
- Stevens-Johnson syndrome
- Seizure
- Eosinophilia
- Nausea
- Rash
- Abdominal pain
- Chills
- Dysuria
- Headache
- Jarisch-Herxheimer reaction
- Pseudomembranous colitis
- Vomiting
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